Department of Family Medicine, Faculty of Medicine, Universiti Kebangsaan Malaysia Medical Centre, Level 14, Preclinical Block, Jalan Yaacob Latiff, Bandar Tun Razak, Cheras, 56000, Kuala Lumpur, Malaysia.
Center for Rehabilitation and Special Needs, Faculty of Health Sciences, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia.
BMC Geriatr. 2020 Feb 18;20(1):70. doi: 10.1186/s12877-020-1453-z.
The delivery of post stroke care is fragmented even in advanced public healthcare systems, globally. Primary care teams are entrusted to provide longer term care for stroke survivors in most developing countries. The integrated Care Pathway for Post Stroke patients (iCaPPS) was designed to guide primary care teams to incorporate further rehabilitation and regular screening for post stroke complications among patients residing at home in communities, using the shared-care approach, especially in areas with limited access to specialist stroke care services. The iCaPPS addressed coordination of rehabilitation and screening for post stroke complications which were absent in the current conventional care of patients managed at public primary care healthcentres. This study aimed to evaluate the cost effectiveness and impact of iCaPPS on quality-adjusted- life-years (QALY) compared with current conventional monitoring at public primary care healthcentres.
A pragmatic healthcentre-based cluster randomised controlled trial-within trial on 151 post stroke patients from 10 public primary care facilities in Peninsular Malaysia was conducted to evaluate QALY of patients managed with iCaPPS (n = 86) vs conventional care (n = 65) for 6 months. Costs from societal perspective were calculated, using combination of top down and activity-based costing methods. The 5-level EQ5D (EQ-5D-5 L) was used to calculate health state utility scores. Cost per QALY and incremental cost effectiveness ratio (ICER) were determined. Differences within groups were determined using Mann-Whitney tests.
Total costs for 6 months treatment with iCaPPS was MYR790.34, while conventional care cost MYR527.22. Median QALY for iCaPPS was 0.55 (0,1.65) compared to conventional care 0.32 (0, 0.73) (z = - 0.21, p = 0.84). Cost per QALY for iCaPPS was MYR1436.98, conventional care was MYR1647.56. The ICER was MYR1144.00, equivalent to 3.7% of per capita GDP (2012 prices).
Management of post stroke patients in the community using iCaPPS costs less per QALY compared to current conventional care and is very cost effective.
Trial Registration number ACTRN12616001322426. Registered 21 September 2016. (Retrospectively registered).
即使在先进的公共医疗体系中,全球范围内的中风后护理服务也存在碎片化现象。在大多数发展中国家,基层医疗团队负责为中风幸存者提供长期护理。综合中风后患者护理路径(iCaPPS)旨在指导基层医疗团队采用共同照护的方法,为居住在社区家中的患者提供进一步的康复和定期筛查中风后并发症服务,特别是在那些难以获得专业中风护理服务的地区。iCaPPS 解决了目前在公共基层医疗保健中心管理的患者常规护理中缺乏的康复和中风后并发症筛查的协调问题。本研究旨在评估 iCaPPS 在质量调整生命年(QALY)方面的成本效益和对中风后患者的影响,与公共基层医疗保健中心目前的常规监测相比。
在马来西亚半岛的 10 个公共基层医疗保健设施中,进行了一项基于医疗中心的集群随机对照试验内试验,共纳入 151 名中风后患者,评估了接受 iCaPPS(n=86)与接受常规护理(n=65)治疗 6 个月的患者的 QALY。采用自上而下和基于活动的成本核算相结合的方法,从社会角度计算成本。使用 EQ5D-5L 量表(EQ-5D-5L)计算健康状态效用得分。确定成本效益比(ICER)和增量成本效益比(ICER)。采用曼-惠特尼检验比较组内差异。
接受 iCaPPS 治疗 6 个月的总费用为 790.34 林吉特,而接受常规护理的费用为 527.22 林吉特。iCaPPS 的中位数 QALY 为 0.55(0,1.65),而常规护理为 0.32(0,0.73)(z=-0.21,p=0.84)。iCaPPS 的每 QALY 成本为 1436.98 林吉特,常规护理为 1647.56 林吉特。iCaPPS 的 ICER 为 1144.00 林吉特,相当于人均国内生产总值(2012 年价格)的 3.7%。
与目前的常规护理相比,使用 iCaPPS 对社区中风后患者进行管理,每 QALY 的成本更低,且非常具有成本效益。
试验注册号 ACTRN12616001322426。2016 年 9 月 21 日注册。(事后注册)。