Division of Pediatrics, Department of Clinical Science, Intervention and Technology and
Department of Learning, Informatics, Management and Ethics, Medical Management Centre, Karolinska Institutet, Stockholm, Sweden.
Pediatrics. 2020 Mar;145(3). doi: 10.1542/peds.2019-1420. Epub 2020 Feb 18.
To compare sleep in young children at different obesity risks, which were based on parental weight, as well as to explore the longitudinal associations of sleep characteristics with adiposity.
In total, 107 children from an obesity prevention project were included, of which 43 had normal-weight parents (low obesity risk) and 64 had overweight and/or obese parents (high obesity risk). Sleep was measured yearly from ages 2 to 6 years by using actigraphy. Five sleep characteristics, that of late sleep, long sleep latency, short sleep duration, low sleep efficiency, and irregular sleep onset, were defined and scored across ages, with a higher score indicating more frequent exposure. The outcome variables, also measured yearly, were BMI score and waist circumference.
There was no difference in sleep patterns among children at different risks. Higher short sleep duration score was associated with a greater increase in BMI score (0.12; 95% confidence interval [CI] 0.01 to 0.25) across ages. Independently of sleep duration, higher late sleep score was associated with greater increases in BMI score (0.16; 95% CI 0.05 to 0.27) and waist circumference (0.60 cm; 95% CI 0.23 to 0.98). Moreover, compared with children at low risk and without habitual late sleep, children at high risk and with habitual late sleep had greater increases in BMI score (0.93; 95% CI 0.40 to 1.45) and waist circumference (3.45 cm; 95% CI 1.78 to 5.12).
More frequent exposures to late sleep were associated with greater increases in adiposity measures from ages 2 to 6 years, particularly in children with obese parents.
比较不同肥胖风险的幼儿的睡眠情况，肥胖风险是基于父母的体重，同时还探讨了睡眠特征与肥胖之间的纵向关联。
共纳入了来自肥胖预防项目的 107 名儿童，其中 43 名儿童的父母体重正常（肥胖风险低），64 名儿童的父母超重和/或肥胖（肥胖风险高）。从 2 岁到 6 岁，每年通过活动记录仪来测量睡眠情况。定义并评估了 5 种睡眠特征，即晚睡、长睡眠潜伏期、短睡眠时间、低睡眠效率和不规则的入睡时间，评分范围为各年龄段，评分越高表示暴露频率越高。每年还测量了身体质量指数（BMI）评分和腰围作为结果变量。
不同风险水平的儿童之间睡眠模式没有差异。较高的短睡眠时间评分与 BMI 评分的增加（0.12；95%置信区间 [CI] 0.01 至 0.25）有关，这种增加在整个年龄段都存在。独立于睡眠时间之外，较高的晚睡评分与 BMI 评分（0.16；95% CI 0.05 至 0.27）和腰围（0.60 厘米；95% CI 0.23 至 0.98）的增加有关。此外，与低风险且没有习惯性晚睡的儿童相比，高风险且有习惯性晚睡的儿童 BMI 评分增加更多（0.93；95% CI 0.40 至 1.45），腰围增加更多（3.45 厘米；95% CI 1.78 至 5.12）。
从 2 岁到 6 岁，频繁暴露于晚睡与肥胖指标的增加有关，尤其是在肥胖父母的儿童中。
