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新西兰植入式心脏复律除颤器及心脏再同步治疗的应用(ANZACS-QI 33)

Implantable cardioverter defibrillator and cardiac resynchronization therapy use in New Zealand (ANZACS-QI 33).

作者信息

Foo Fang Shawn, Lee Mildred, Looi Khang-Li, Larsen Peter, Clare Geoffrey C, Heaven David, Stiles Martin K, Voss Jamie, Boddington Dean, Jackson Rod, Kerr Andrew J

机构信息

Department of Cardiology Middlemore Hospital Auckland New Zealand.

Department of Cardiology Auckland City Hospital Auckland New Zealand.

出版信息

J Arrhythm. 2019 Oct 6;36(1):153-163. doi: 10.1002/joa3.12244. eCollection 2020 Feb.

DOI:10.1002/joa3.12244
PMID:32071634
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7011834/
Abstract

BACKGROUND

The ANZACS-QI Cardiac Implanted Device Registry (ANZACS-QI DEVICE) collects nationwide data on cardiac implantable electronic devices in New Zealand (NZ). We used the registry to describe contemporary NZ use of implantable cardioverter defibrillator (ICD) and cardiac resynchronization therapy (CRT).

METHODS

All ICD and CRT Pacemaker implants recorded in ANZACS-QI DEVICE between 1 January 2014 and 31 December 2017 were analyzed.

RESULTS

Of 1579 ICD implants, 1152 (73.0%) were new implants, including 49.0% for primary prevention and 51.0% for secondary prevention. In both groups, median age was 62 years and patients were predominantly male (81.4% and 79.2%, respectively). Most patients receiving a primary prevention ICD had a history of clinical heart failure (80.4%), NYHA class II-III symptoms (77.1%) and LVEF ≤35% (96.9%). In the secondary prevention ICD cohort, 88.4% were for sustained ventricular tachycardia or survived cardiac arrest from ventricular arrhythmia. Compared to primary prevention CRT Defibrillators (n = 155), those receiving CRT Pacemakers (n = 175) were older (median age 74 vs 66 years) and more likely to be female (38.3% vs 19.4%). Of the 427 (27.0%) ICD replacements (mean duration 6.3 years), 46.6% had received appropriate device therapy while 17.8% received inappropriate therapy. The ICD implant rate was 119 per million population with regional variation in implant rates, ratio of primary prevention ICD implants, and selection of CRT modality.

CONCLUSION

In contemporary NZ practice three-quarters of ICD implants were new implants, of which half were for primary prevention. The majority met current guideline indications. Patients receiving CRT pacemaker were older and more likely to be female.

摘要

背景

澳新军团质量改进心脏植入设备注册库(ANZACS-QI DEVICE)收集了新西兰全国范围内心脏植入式电子设备的数据。我们利用该注册库描述了新西兰当代植入式心脏复律除颤器(ICD)和心脏再同步治疗(CRT)的使用情况。

方法

对2014年1月1日至2017年12月31日期间ANZACS-QI DEVICE记录的所有ICD和CRT起搏器植入情况进行分析。

结果

在1579例ICD植入病例中,1152例(73.0%)为新植入,其中49.0%用于一级预防,51.0%用于二级预防。两组的中位年龄均为62岁,患者以男性为主(分别为81.4%和79.2%)。大多数接受一级预防ICD的患者有临床心力衰竭病史(80.4%)、纽约心脏病协会II-III级症状(77.1%)和左心室射血分数≤35%(96.9%)。在二级预防ICD队列中,88.4%用于持续性室性心动过速或室性心律失常导致的心脏骤停幸存者。与一级预防CRT除颤器(n = 155)相比,接受CRT起搏器(n = 175)的患者年龄更大(中位年龄74岁对66岁),女性比例更高(38.3%对19.4%)。在427例(27.0%)ICD更换病例中(平均持续时间6.3年),46.6%接受了适当的设备治疗,17.8%接受了不适当的治疗。ICD植入率为每百万人口119例,植入率、一级预防ICD植入比例和CRT模式选择存在地区差异。

结论

在当代新西兰的实践中,四分之三的ICD植入为新植入,其中一半用于一级预防。大多数符合当前指南指征。接受CRT起搏器的患者年龄更大,女性比例更高。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f7bd/7011834/6462c14ef882/JOA3-36-153-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f7bd/7011834/a1070bf5d1ad/JOA3-36-153-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f7bd/7011834/6462c14ef882/JOA3-36-153-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f7bd/7011834/a1070bf5d1ad/JOA3-36-153-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f7bd/7011834/6462c14ef882/JOA3-36-153-g002.jpg

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