Department of Orthopaedics, The Affiliated Hospital of Zunyi Medical University, Huichuan District, Dalian Road, Zunyi, Guizhou, China.
Department of Orthopaedics, The Second Affiliated Hospital of Zunyi Medical University, Xinpu New Area, Zunyi, Guizhou, China.
Biomed Res Int. 2020 Jan 30;2020:1468457. doi: 10.1155/2020/1468457. eCollection 2020.
Tuberculosis (TB) is an endemic disease in Guizhou. Spinal TB accounts for approximately 50% cases of skeletal TB. The purpose of this study was to investigate the characteristics and management of patients treated for spinal TB in a certain hospital and to provide guidance for the prevention and treatment of spinal TB.
The clinic records of all patients diagnosed with spinal tuberculosis in a teaching hospital between January 2010 and December 2018 were collected. The epidemiology, clinical characteristics, imaging and laboratory findings, treatment methods, and prognosis were recorded and analyzed.
During this nine-year period, 597 patients with spinal TB were identified. There were 313 males and 284 females with an average age of 43 years. The largest number of patients fell in the age group of 21-30 years; mean time from symptom onset to diagnosis in the hospital was 17 months. Back pain was the main clinical manifestation (89.34%). The most common imaging technique was computed tomography (CT, 96.80%), followed by magnetic resonance imaging (MRI, 84.01%). Majority of the lesions involved the lumbar spine (47.30%), followed by the thoracic spine (40.95%). 178 (29.82%) patients in this study had varying degrees of neurological impairment. 22.78% of the patients selected conservative treatment, and surgical treatment was performed in 483 patients (80.90%).
The incidence of spinal TB was generally on the rise throughout the study period. After diagnosed with spinal TB, all patients got appropriate treatment and achieved good efficacy, but most of the patients did not pay much attention to the disease and receive timely treatment. Thus, it is essential to strengthen the TB preventive strategies, improve the health awareness of residents and universal resident health examination.
结核病（TB）是贵州的地方性疾病。脊柱结核约占骨骼结核的 50%。本研究旨在调查某医院治疗脊柱结核患者的特点和管理，为脊柱结核的防治提供指导。
收集 2010 年 1 月至 2018 年 12 月某教学医院确诊为脊柱结核的所有患者的临床记录。记录和分析流行病学、临床特征、影像学和实验室发现、治疗方法和预后。
在这九年期间，共发现 597 例脊柱结核患者。男性 313 例，女性 284 例，平均年龄 43 岁。患者数量最多的年龄段为 21-30 岁；平均住院时间为 17 个月。背痛是主要的临床表现（89.34%）。最常用的影像学技术是计算机断层扫描（CT，96.80%），其次是磁共振成像（MRI，84.01%）。大多数病变累及腰椎（47.30%），其次是胸椎（40.95%）。本研究中 178 例（29.82%）患者有不同程度的神经功能障碍。22.78%的患者选择保守治疗，483 例（80.90%）患者接受手术治疗。
在整个研究期间，脊柱结核的发病率普遍呈上升趋势。诊断为脊柱结核后，所有患者均得到了适当的治疗，疗效良好，但大多数患者对该病重视不够，未能及时治疗。因此，加强结核病防治策略，提高居民的健康意识和全民健康检查十分必要。
