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机器人辅助微创经胸食管切除术(Ivor Lewis):100 例连续患者的良好结果(欧洲经验)。

Robot-Assisted Minimally Invasive Esophagectomy with Intrathoracic Anastomosis (Ivor Lewis): Promising Results in 100 Consecutive Patients (the European Experience).

机构信息

Department of General, Visceral and Transplant Surgery, University Medical Center of the Johannes Gutenberg University, Langenbeckstrasse 1, D-55131, Mainz, Germany.

Department of Surgery, University Medical Center Utrecht, Utrecht, Netherlands.

出版信息

J Gastrointest Surg. 2021 Jan;25(1):1-8. doi: 10.1007/s11605-019-04510-8. Epub 2020 Feb 18.

Abstract

BACKGROUND

Robot-assisted minimally invasive esophagectomy (RAMIE) with intrathoracic anastomosis is gaining popularity as a treatment for esophageal cancer. The aim of this study was to describe postoperative complications and short-term oncologic outcomes for RAMIE procedures using the da Vinci Xi robotic system 4-arm technique.

METHODS

Data of 100 consecutive patients with esophageal or gastro-esophageal junction carcinoma undergoing modified Ivor Lewis esophagectomy were prospectively collected. All operations were performed by the same surgeon using an identical intrathoracic anastomotic reconstruction technique with the same perioperative management. Intraoperative and postoperative complications were graded according to Esophagectomy Complications Consensus Group (ECCG) definitions.

RESULTS

Mean duration was 416 min (±80); 70% of patients had an uncomplicated postoperative recovery. Pulmonary complications were observed in 17% of patients. Anastomotic leakage was observed in 8% of patients. Median ICU stay was 1 day and median overall postoperative hospital stay was 11 days. The 30-day mortality was 1%; 90-day mortality was 3%. A R0 resection was reached in 92% of patients with a median number of 29 dissected lymph nodes. All patients had at least 7 months of follow-up with a median follow-up of 17 months. Median overall survival was not reached yet.

CONCLUSION

RAMIE with intrathoracic anastomosis (Ivor Lewis) for esophageal or gastro-esophageal junction cancer was technically feasible and safe. Postoperative complications and short-term oncologic results were comparable to the highest international standards nowadays.

摘要

背景

机器人辅助微创食管切除术(RAMIE)联合胸内吻合术作为食管癌的治疗方法越来越受欢迎。本研究旨在描述使用达芬奇 Xi 机器人系统 4 臂技术进行 RAMIE 手术后的术后并发症和短期肿瘤学结果。

方法

前瞻性收集了 100 例连续接受改良 Ivor Lewis 食管切除术的食管或胃食管交界处癌患者的数据。所有手术均由同一位外科医生使用相同的胸腔内吻合重建技术和相同的围手术期管理进行。根据食管切除术并发症共识小组(ECCG)的定义对术中及术后并发症进行分级。

结果

平均手术时间为 416 分钟(±80);70%的患者术后恢复顺利。17%的患者发生肺部并发症。8%的患者发生吻合口漏。中位 ICU 住院时间为 1 天,中位总术后住院时间为 11 天。30 天死亡率为 1%;90 天死亡率为 3%。92%的患者达到 R0 切除,中位清扫淋巴结数为 29 个。所有患者的随访时间至少为 7 个月,中位随访时间为 17 个月。中位总生存期尚未达到。

结论

对于食管或胃食管交界处癌,行 RAMIE 联合胸内吻合术(Ivor Lewis)是可行且安全的。术后并发症和短期肿瘤学结果与目前最高的国际标准相当。

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