点击- TambJamines 作为高效且可调的生物活性阴离子转运体。
Click-tambjamines as efficient and tunable bioactive anion transporters.
机构信息
Departamento de Química, Universidad de Burgos, Burgos 09001, Spain.
UOC Genetica Medica, IRCSS Istituto Giannina Gaslini, Genova, Italy.
出版信息
Chem Commun (Camb). 2020 Mar 12;56(21):3218-3221. doi: 10.1039/d0cc00643b.
PMID:32073062
Abstract
A novel class of transmembrane anion carriers, the click-tambjamines, display remarkable anionophoric activities in model liposomes and living cells. The versatility of this building block for the generation of molecular diversity offers promise to develop future drugs based on this design.
摘要
一类新型的跨膜阴离子载体，即点击 Tambjamines，在模型脂质体和活细胞中表现出显著的阴离子载体活性。这种构建模块在产生分子多样性方面的多功能性为基于该设计开发未来药物提供了希望。
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