胎儿肠扩张中肠道病变的产前预测指标
Antenatal predictors of intestinal pathologies in fetal bowel dilatation.
作者信息
Huang Lan, Huang Danping, Wang Hongying, Zhang Xiangxiang, Yu Hongkui, Yang Pan
机构信息
Ultrasound Department, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China.
出版信息
J Paediatr Child Health. 2020 Jul;56(7):1097-1100. doi: 10.1111/jpc.14825. Epub 2020 Feb 19.
AIM
Fetal bowel dilatation (FBD) in the late trimester of pregnancy can be related with varies of prognosis. Our aims were to obtain antenatal factors that might have relevance for the distinct prognosis with FBD.
METHODS
Seven features of 68 pregnancies presented with FBD were assessed. The best cut-off value to predict intestinal outcomes was selected using receiver-operating characteristics curves, and the effective variables were included into a logistic regression model.
RESULTS
The best cut-off valves to predict intestinal pathologies were 14.5 mm of fetus dilated loop and 37.7 weeks of gestational age at delivery, respectively. The congenital gastrointestinal tract anomalies included 24 cases (92.3%) of intestine atresia, 1 case (3.85%) of small intestine volvulus and 1 case (3.85%) of midgut malrotation.
CONCLUSION
Fetal dilated loops and gestational age at delivery are both an independent risk factor for predicting intestinal pathologies of newborns, which should arouse high attention.
目的
妊娠晚期胎儿肠管扩张（FBD）可能与多种预后相关。我们的目的是获取可能与FBD不同预后相关的产前因素。
方法
评估了68例出现FBD的妊娠的七个特征。使用受试者工作特征曲线选择预测肠道结局的最佳截断值，并将有效变量纳入逻辑回归模型。
结果
预测肠道病变的最佳截断值分别为胎儿扩张肠袢14.5毫米和分娩时孕周37.7周。先天性胃肠道畸形包括肠闭锁24例（92.3%）、小肠扭转1例（3.85%）和中肠旋转不良1例（3.85%）。
结论
胎儿扩张肠袢和分娩时孕周都是预测新生儿肠道病变的独立危险因素，应引起高度重视。
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