Kong W J, Gu X H, Sun J
Department of Prosthodontics, The First Affiliated Hospital, Zhejiang University, School of Medicine, Hangzhou 310003, China.
Zhonghua Kou Qiang Yi Xue Za Zhi. 2020 Feb 9;55(2):135-138. doi: 10.3760/cma.j.issn.1002-0098.2020.02.013.
Establishing a stable resin-dentin hybrid layer is an effective method to improve the adhesion durability of the restoration. The biomodification of dentin by cross-linkers can enhance the mechanical properties of collagen and resistance to enzymatic hydrolysis while, inhibiting the process of demineralization and promoting the remineralization of dentin, which has the potential clinical applicability of preventing dental caries and improving adhesive property. This review summarizes the biomodification of dentin type Ⅰ collagen by different cross-linkers.
建立稳定的树脂-牙本质混合层是提高修复体粘结耐久性的有效方法。交联剂对牙本质进行生物改性可增强胶原蛋白的机械性能和抗酶水解能力，同时抑制脱矿过程并促进牙本质再矿化，这在预防龋齿和改善粘结性能方面具有潜在的临床应用价值。本文综述了不同交联剂对Ⅰ型牙本质胶原的生物改性。
