Wilson D, Berardesca E, Maibach H I
Department of Dermatology, University of California Medical School, San Francisco.
Br J Dermatol. 1988 Nov;119(5):647-52. doi: 10.1111/j.1365-2133.1988.tb03478.x.
In vivo transepidermal water loss studies are characterized by large inter-individual variability and biased by environmental effects and eccrine sweating. An in vitro technique for measuring transepidermal water loss (TEWL) was used to compare TEWL in two racial groups--blacks and whites. In both groups a significant correlation between skin temperature and increased TEWL was found (P less than 0.01). Furthermore, black skin had a significantly higher mean TEWL than white skin, corrected log TEWL 2.79 and 2.61 micrograms/cm2/h, respectively. The difference in TEWL between the groups could because measurements were made in the absence of eccrine sweating and other vital functions. The higher TEWL in black skin could be explained on the basis of a thermoregulatory mechanism. The anatomical and physiological differences in the stratum corneum between different races are discussed.
体内经表皮水分流失研究具有个体间差异大的特点，且受环境影响和外分泌汗腺出汗的影响存在偏差。采用一种体外测量经表皮水分流失（TEWL）的技术来比较两个种族群体——黑人和白人的TEWL。在两个群体中均发现皮肤温度与TEWL升高之间存在显著相关性（P<0.01）。此外，黑人皮肤的平均TEWL显著高于白人皮肤，校正后的对数TEWL分别为2.79和2.61微克/平方厘米/小时。两组之间TEWL的差异可能是因为测量是在没有外分泌汗腺出汗和其他重要功能的情况下进行的。黑人皮肤中较高的TEWL可以基于体温调节机制来解释。讨论了不同种族之间角质层的解剖学和生理学差异。
