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瓦伦贝格综合征中的角膜受累:病例报告与文献综述

Corneal Involvement in Wallenberg Syndrome: Case Report and Literature Review.

作者信息

Pellegrini Francesco, Interlandi Emanuela, Cuna Alessandra, Mandarà Erika, Lee Andrew G

机构信息

Department of Ophthalmology, Conegliano Hospital, Conegliano, Italy.

Department of Ophthalmology, "Ospedale Del Mare", Naples, Italy.

出版信息

Neuroophthalmology. 2019 Apr 8;44(1):54-58. doi: 10.1080/01658107.2019.1602147. eCollection 2020 Feb.

Abstract

A 47-year-old man with Wallenberg syndrome after a stroke in the territory of the left vertebrobasilar artery and posterior inferior cerebellar artery, presented a week later complaining of visual loss in the left eye. Examination showed corneal anaesthesia associated with a neurotrophic corneal epithelial defect. Corneal involvement secondary to trigeminal neuropathy in Wallenberg syndrome is not frequently reported and may lead to epithelial erosion and neurotrophic keratopathy. Clinicians should be aware that visual loss can occur from a neurogenic basis (e.g., Wallenberg syndrome) due to neurotrophic keratopathy. The use of cocaine, a potential cause of neurotrophic keratopathy, should also be suspected in the appropriate clinical scenario.

摘要

一名47岁男性,在左椎基底动脉和小脑后下动脉区域中风后出现延髓背外侧综合征,一周后前来就诊,主诉左眼视力丧失。检查发现角膜麻醉伴有神经营养性角膜上皮缺损。延髓背外侧综合征继发于三叉神经病变的角膜受累情况并不常见,可能导致上皮糜烂和神经营养性角膜病变。临床医生应意识到,神经营养性角膜病变可导致神经源性视力丧失(如延髓背外侧综合征)。在适当的临床情况下,还应怀疑使用可卡因这一神经营养性角膜病变的潜在病因。

相似文献

1
Corneal Involvement in Wallenberg Syndrome: Case Report and Literature Review.瓦伦贝格综合征中的角膜受累:病例报告与文献综述
Neuroophthalmology. 2019 Apr 8;44(1):54-58. doi: 10.1080/01658107.2019.1602147. eCollection 2020 Feb.
3
Unilateral punctate keratitis secondary to Wallenberg Syndrome.继发于延髓背外侧综合征的单侧点状角膜炎
Korean J Ophthalmol. 2014 Jun;28(3):278-83. doi: 10.3341/kjo.2014.28.3.278. Epub 2014 May 19.
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Hitting a Wall: An Ambiguous Case of Wallenberg Syndrome.陷入困境:一例不典型的延髓背外侧综合征
Cureus. 2021 Jul 8;13(7):e16268. doi: 10.7759/cureus.16268. eCollection 2021 Jul.

本文引用的文献

5
Unilateral punctate keratitis secondary to Wallenberg Syndrome.继发于延髓背外侧综合征的单侧点状角膜炎
Korean J Ophthalmol. 2014 Jun;28(3):278-83. doi: 10.3341/kjo.2014.28.3.278. Epub 2014 May 19.
6
Diagnosis and management of neurotrophic keratitis.神经营养性角膜炎的诊断与治疗
Clin Ophthalmol. 2014 Mar 19;8:571-9. doi: 10.2147/OPTH.S45921. eCollection 2014.
7
Neurotrophic keratitis.神经营养性角膜炎。
Ophthalmologica. 2014;231(4):191-7. doi: 10.1159/000354380. Epub 2013 Oct 2.
10
Corneal nerves: structure, contents and function.角膜神经:结构、成分与功能。
Exp Eye Res. 2003 May;76(5):521-42. doi: 10.1016/s0014-4835(03)00050-2.

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