Department of Radiology, Children's Hospital of Philadelphia, Perelman School of Medicine, University of Pennsylvania, 3401 Civic Center Blvd., Philadelphia, PA, 19104, USA.
Pediatr Radiol. 2020 May;50(5):607-617. doi: 10.1007/s00247-019-04578-z. Epub 2020 Feb 19.
Children with malignancies undergo recurrent imaging as part of tumor diagnosis, staging and therapy response assessment. Simultaneous positron emission tomography (PET) and magnetic resonance (MR) allows for decreased radiation exposure and acts as a one-stop shop for disease in which MR imaging is required. Nevertheless, PET/MR is still less readily available than PET/CT across institutions. This article serves as a guide to successful implementation of a clinical pediatric PET/MR program based on our extensive clinical experience. Challenges include making scanners more affordable and increasing patient throughput by decreasing total scan time. With improvements in workflow and robust acquisition protocols, PET/MR imaging is expected to play an increasingly important role in pediatric oncology.
患有恶性肿瘤的儿童需要进行反复的影像学检查，这是肿瘤诊断、分期和治疗反应评估的一部分。正电子发射断层扫描（PET）和磁共振（MR）的同步检查可以减少辐射暴露，并且可以一站式完成需要 MR 成像的疾病诊断。然而，与 PET/CT 相比，PET/MR 在医疗机构中的应用仍然较少。基于我们丰富的临床经验，本文旨在为成功实施临床儿科 PET/MR 项目提供指导。面临的挑战包括降低扫描仪的成本，以及通过减少总扫描时间来提高患者吞吐量。通过改进工作流程和强大的采集方案，PET/MR 成像有望在儿科肿瘤学中发挥越来越重要的作用。
