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经前胸入路免气腹内镜选择性侧颈清扫术与传统开放手术治疗乳头状甲状腺癌的对比研究

Comparative study of gasless endoscopic selective lateral neck dissection via the anterior chest approach versus conventional open surgery for papillary thyroid carcinoma.

作者信息

Lin Peiliang, Liang Faya, Cai Qian, Han Ping, Chen Renhui, Xiao Zhiwen, Wang Jingyi, Huang Xiaoming

机构信息

Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Department of Otolaryngology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, 33, Yingfeng Road, Guangzhou, 510289, Guangdong, China.

出版信息

Surg Endosc. 2021 Feb;35(2):693-701. doi: 10.1007/s00464-020-07434-6. Epub 2020 Feb 19.

Abstract

BACKGROUND

Although there has been increasing interest in aesthetical approaches for treating patients with papillary thyroid carcinoma (PTC), there have been no studies comparing the safety and effectiveness of gasless endoscopic selective lateral neck dissection (SLND) via the anterior chest approach (ACA) with that of conventional open surgery (OPEN) for papillary thyroid carcinoma.

METHODS

A total of 91 patients with PTC who underwent either gasless endoscopic thyroidectomy, central compartment neck dissection and SLND via the ACA or conventional open surgery between Nov. 2008 to Dec. 2018 were included. Primary outcomes and demographic data were compared between the two groups.

RESULTS

Thirty-one patients were in the ACA group and 60 were in the OPEN group. The ACA group was younger and had a longer operative time but less intraoperative hemorrhage (P < 0.001 for all). There were no differences in other clinicopathological features. During the median follow-up of 48 months (ACA group) and 35 months (OPEN group), no recurrence on US/CT was found. The patients in the ACA group had better cosmetic results assessed postoperatively.

CONCLUSION

It appeared that gasless endoscopic selective lateral neck dissection via the anterior chest approach achieved comparable safety and effectiveness as conventional open surgery for PTC and resulted in better cosmetic results.

摘要

背景

尽管对于采用美学方法治疗甲状腺乳头状癌(PTC)患者的兴趣日益浓厚,但尚无研究比较经前胸入路(ACA)的无气内镜选择性侧颈淋巴结清扫术(SLND)与传统开放手术(OPEN)治疗甲状腺乳头状癌的安全性和有效性。

方法

纳入2008年11月至2018年12月期间接受无气内镜甲状腺切除术、中央区颈淋巴结清扫术及经ACA的SLND或传统开放手术的91例PTC患者。比较两组的主要结局和人口统计学数据。

结果

ACA组31例患者,OPEN组60例患者。ACA组患者更年轻,手术时间更长,但术中出血更少(所有P值均<0.001)。其他临床病理特征无差异。在ACA组48个月和OPEN组35个月的中位随访期间,超声/CT检查未发现复发。ACA组患者术后美容效果评估更好。

结论

经前胸入路的无气内镜选择性侧颈淋巴结清扫术在治疗PTC方面似乎与传统开放手术具有相当的安全性和有效性,且美容效果更好。

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