Xu Qiyin, Zhu Li, Chen Weiping, Peng Weibin
Department of Gastrointestinal Surgery, The First People's Hospital of Yibin, Yibin, China.
Ann Surg Treat Res. 2024 Sep;107(3):127-135. doi: 10.4174/astr.2024.107.3.127. Epub 2024 Aug 26.
This study was performed to compare the therapeutic efficacy of endoscopic surgery and open surgery and their effects on postoperative blood coagulation state in patients with thyroid cancer, and to provide evidence for the prevention measurement of thrombosis in the perioperative period.
One hundred patients with thyroid cancer who received treatment in our hospital from January 2021 to December 2021, were randomly divided into an endoscopic group and an open surgery group, with 50 patients in each group. The patients in the open surgery group were treated by traditional open surgery, while patients in the endoscopic group accepted endoscopic surgery. The clinically therapeutic effect and blood coagulation of the 2 groups were compared.
Intraoperative blood loss and length of hospital stay were lower, and operative time was longer in the endoscopic group than in the open surgery group (P < 0.05). The 24-hour postoperative fibrinogen and D-dimer levels were higher in both groups than in the preoperative period, while PT was shorter (P < 0.05). There were no significant differences in postoperative complications and follow-up between the 2 groups (P > 0.05), but the incidence of complications, postoperative metastases, and thrombosis was relatively low in the endoscopic group.
In the treatment of patients with thyroid cancer, endoscopic surgery has the advantages of less blood loss, fewer complications, and so on. Endoscopic and open surgery can lead to a hypercoagulable state, but the effect of endoscopic surgery is better than that of open surgery.
本研究旨在比较甲状腺癌患者内镜手术与开放手术的治疗效果及其对术后血液凝固状态的影响,为围手术期血栓形成的预防措施提供依据。
选取2021年1月至2021年12月在我院接受治疗的100例甲状腺癌患者,随机分为内镜组和开放手术组,每组50例。开放手术组患者采用传统开放手术治疗,内镜组患者接受内镜手术。比较两组的临床治疗效果和血液凝固情况。
内镜组术中出血量和住院时间低于开放手术组,手术时间长于开放手术组(P<0.05)。两组术后24小时纤维蛋白原和D-二聚体水平均高于术前,而PT缩短(P<0.05)。两组术后并发症和随访情况差异无统计学意义(P>0.05),但内镜组并发症、术后转移和血栓形成的发生率相对较低。
在甲状腺癌患者的治疗中,内镜手术具有出血量少、并发症少等优点。内镜手术和开放手术均可导致高凝状态,但内镜手术的效果优于开放手术。