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阿德勒克雷茨氏菌产雌马酚菌IPLA 37004的基因组序列草图，该菌为一株不将大豆苷元转化为雌马酚的人肠道菌株。

Draft Genome Sequence of Adlercreutzia equolifaciens IPLA 37004, a Human Intestinal Strain That Does Not Produce Equol from Daidzein.

作者信息

Vázquez Lucía, Flórez Ana Belén, Mayo Baltasar

机构信息

Departamento de Microbiología y Bioquímica, Instituto de Productos Lácteos de Asturias (IPLA-CSIC), Villaviciosa, Asturias, Spain.

Instituto de Investigación Sanitaria del Principado de Asturias (ISPA), Oviedo, Asturias, Spain.

出版信息

Microbiol Resour Announc. 2020 Feb 20;9(8):e01537-19. doi: 10.1128/MRA.01537-19.

DOI:10.1128/MRA.01537-19
PMID:32079634
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7033271/
Abstract

Equol is an intestinal bacterial metabolite derived from the isoflavone daidzein and has beneficial health effects. Most equol producers belong to the family , which includes species such as Here, we report the draft genome sequence of IPLA 37004, a human isolate that does not produce equol.

摘要

雌马酚是一种由异黄酮大豆苷元衍生而来的肠道细菌代谢产物，具有有益的健康效应。大多数雌马酚产生菌属于 科，其中包括 等物种。在此，我们报告了IPLA 37004的基因组草图序列，这是一株不产生雌马酚的人类分离菌株。

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本文引用的文献

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Equol: A Bacterial Metabolite from The Daidzein Isoflavone and Its Presumed Beneficial Health Effects.大豆苷元：来自大豆异黄酮的细菌代谢产物及其推测的有益健康作用。
Nutrients. 2019 Sep 16;11(9):2231. doi: 10.3390/nu11092231.
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RefSeq: an update on prokaryotic genome annotation and curation.RefSeq：原核生物基因组注释和管理的最新进展。
Nucleic Acids Res. 2018 Jan 4;46(D1):D851-D860. doi: 10.1093/nar/gkx1068.
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The antioxidant activity of daidzein metabolites, O‑desmethylangolensin and equol, in HepG2 cells.黄豆苷元代谢产物O-去甲基安哥拉紫檀素和雌马酚在HepG2细胞中的抗氧化活性。
Mol Med Rep. 2014 Jan;9(1):328-32. doi: 10.3892/mmr.2013.1752. Epub 2013 Oct 23.
5
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Genome Announc. 2013 Sep 19;1(5):e00742-13. doi: 10.1128/genomeA.00742-13.
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SPAdes: a new genome assembly algorithm and its applications to single-cell sequencing.SPAdes：一种新的基因组组装算法及其在单细胞测序中的应用
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Mauve: multiple alignment of conserved genomic sequence with rearrangements.Mauve：带重排的保守基因组序列多重比对。
Genome Res. 2004 Jul;14(7):1394-403. doi: 10.1101/gr.2289704.
8
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Biol Reprod. 2004 Sep;71(3):966-72. doi: 10.1095/biolreprod.104.029512. Epub 2004 May 19.