R.A. Steinman is associate professor of medicine, director, Medical Scientist Training Program and Physician Scientist Training Program, and associate dean, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania; ORCID: https://orcid.org/0000-0002-8354-418X.
C.N. Proulx is evaluation coordinator, Clinical and Translational Science Institute and Department of General Internal Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania; ORCID: https://orcid.org/0000-0001-9269-2355.
Acad Med. 2020 Sep;95(9):1373-1381. doi: 10.1097/ACM.0000000000003197.
The University of Pittsburgh School of Medicine Physician Scientist Training Program (PSTP) is a 5-year medical student training program designed to prepare the next generation of MD-only physician-scientists engaging in preclinical research. This article provides an overview of the program, including the novel longitudinal structure and competency goals, which facilitate success and persistence in a laboratory-based physician-scientist career. The authors present data on 81 medical students accepted to the program from academic year 2007-2008 through 2018-2019. Extrinsic outcomes, such as publications, grant funding, and residency matching, indicate that PSTP trainees have actively generated research deliverables. A majority of eligible PSTP trainees have earned Howard Hughes Medical Institute Medical Research Fellow funding. PSTP students have produced a mean of 1.6 first-authored publications (median, 1.0) and a mean of 5.1 total publications (median, 4.0) while in medical school and have authored 0.9 publications per year as residents/fellows, excluding internship. Nearly 60% of PSTP students (26/46) have matched to top-10 National Institutes of Health-funded residency programs in their specialty (based on Blue Ridge Institute rankings). PSTP alumni are twice as likely as their classmates to match into research-heavy departments and to publish first-authored papers. Results of a 2018 program evaluation survey indicate that intrinsic outcomes, such as confidence in research skills, significantly correlate with extrinsic outcomes. The program continues to evolve to maximize both scientific agency and career navigation skills in participants. This medical student PSTP model has potential to expand the pool of physician-scientist researchers in preclinical research beyond the capacity of dedicated MD-PhD and postgraduate training programs.
匹兹堡大学医学院医师科学家培训计划（PSTP）是一个为期 5 年的医学生培训计划，旨在培养从事临床前研究的下一代仅拥有医学博士学位的医师科学家。本文概述了该计划，包括新颖的纵向结构和能力目标，这些结构和目标有助于在以实验室为基础的医师科学家职业中取得成功和坚持。作者介绍了 2007-2008 学年至 2018-2019 学年期间 81 名被该计划录取的医学生的数据。外在成果，如出版物、资助和住院医师匹配情况，表明 PSTP 学员积极产生了研究成果。大多数符合条件的 PSTP 学员都获得了霍华德休斯医学研究所医学研究员基金。PSTP 学生在医学院期间平均发表 1.6 篇第一作者论文（中位数为 1.0）和 5.1 篇总论文（中位数为 4.0），作为住院医师/研究员每年发表 0.9 篇论文，不包括实习。近 60%的 PSTP 学生（26/46）在其专业领域匹配到前 10 名获得美国国立卫生研究院资助的住院医师培训项目（基于蓝岭研究所排名）。与同班同学相比，PSTP 校友更有可能进入以研究为重点的部门，并发表第一作者论文。2018 年计划评估调查的结果表明，内在成果，如对研究技能的信心，与外在成果显著相关。该计划继续发展，以使参与者的科学机构和职业导航技能最大化。这种医学生 PSTP 模式有可能在临床前研究中扩大医师科学家研究人员的队伍，超过专门的 MD-PhD 和研究生培训计划的能力。
