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持续充气和间歇性正压通气对新生儿支气管肺发育不良或死亡的影响：一项系统评价方案

Effect of sustained inflations and intermittent positive pressure ventilation on bronchopulmonary dysplasia or death among neonatal: A protocol for systematic review.

作者信息

Guo Yue, Jiang Yan, Tang Hanbo, Fan Wenjuan, Ai Chenchen, Liu Ping

机构信息

Gansu Provincial Maternity and Child-Care Hospital, Lanzhou, China.

出版信息

Medicine (Baltimore). 2020 Feb;99(8):e19084. doi: 10.1097/MD.0000000000019084.

DOI:10.1097/MD.0000000000019084
PMID:32080082
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7034723/
Abstract

BACKGROUND

Sustained Inflations (SI) and Intermittent Positive Pressure Ventilation (IPPV) are two interventions to prevent Bronchopulmonary dysplasia (BPD). The aim of this study is to assess the effect of these two interventions.

METHODS

The databases of PubMed, EMBASE, and Cochrane Central Register of Controlled Trials (CENTRAL) will be comprehensively searched from inception to September 2019. All RCTs and quasi-RCTs which compare the efficacy of SI vs IPPV among preterm infants are eligible. We will assess the methodological quality using the Cochrane Handbook version 5.1.0. A meta-analysis will be performed using RevMan 5.3 software and the results will be presented using risk ratios (RRs) and 95% confidence intervals (CIs).

CONCLUSIONS

This study will provide strong evidence for assessing the effect of SI and IPPV on BPD or death among preterm infants.

PROSPERO REGISTRATION NUMBER

CRD42019135816.

摘要

背景

持续充气（SI）和间歇正压通气（IPPV）是预防支气管肺发育不良（BPD）的两种干预措施。本研究旨在评估这两种干预措施的效果。

方法

全面检索PubMed、EMBASE和Cochrane对照试验中央注册库（CENTRAL）数据库，检索时间从数据库建立至2019年9月。所有比较SI与IPPV在早产儿中疗效的随机对照试验（RCT）和半随机对照试验（quasi-RCT）均符合纳入标准。我们将使用Cochrane手册5.1.0版评估方法学质量。使用RevMan 5.3软件进行荟萃分析，并使用风险比（RRs）和95%置信区间（CIs）呈现结果。

结论

本研究将为评估SI和IPPV对早产儿BPD或死亡的影响提供有力证据。

PROSPERO注册号：CRD42019135816。

相似文献

1
Effect of sustained inflations and intermittent positive pressure ventilation on bronchopulmonary dysplasia or death among neonatal: A protocol for systematic review.持续充气和间歇性正压通气对新生儿支气管肺发育不良或死亡的影响：一项系统评价方案
Medicine (Baltimore). 2020 Feb;99(8):e19084. doi: 10.1097/MD.0000000000019084.
2
Sustained inflations and avoiding mechanical ventilation to prevent death or bronchopulmonary dysplasia: a meta-analysis.持续膨胀和避免机械通气以预防死亡或支气管肺发育不良：一项荟萃分析。
Eur Respir Rev. 2018 Nov 28;27(150). doi: 10.1183/16000617.0083-2018. Print 2018 Dec 31.
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本文引用的文献

1
Effect of Sustained Inflations vs Intermittent Positive Pressure Ventilation on Bronchopulmonary Dysplasia or Death Among Extremely Preterm Infants: The SAIL Randomized Clinical Trial.持续充气与间歇正压通气对极早产儿支气管肺发育不良或死亡的影响：SAIL 随机临床试验。
JAMA. 2019 Mar 26;321(12):1165-1175. doi: 10.1001/jama.2019.1660.
2
Sustained inflations and avoiding mechanical ventilation to prevent death or bronchopulmonary dysplasia: a meta-analysis.持续膨胀和避免机械通气以预防死亡或支气管肺发育不良：一项荟萃分析。
Eur Respir Rev. 2018 Nov 28;27(150). doi: 10.1183/16000617.0083-2018. Print 2018 Dec 31.
3
Association between prospective registration and overall reporting and methodological quality of systematic reviews: a meta-epidemiological study.前瞻性注册与系统评价的总体报告和方法学质量之间的关联：一项meta 流行病学研究。
J Clin Epidemiol. 2018 Jan;93:45-55. doi: 10.1016/j.jclinepi.2017.10.012. Epub 2017 Oct 31.
4
The economic impact of prematurity and bronchopulmonary dysplasia.早产儿和支气管肺发育不良的经济学影响。
Eur J Pediatr. 2017 Dec;176(12):1587-1593. doi: 10.1007/s00431-017-3009-6. Epub 2017 Sep 9.
5
Sustained versus standard inflations during neonatal resuscitation to prevent mortality and improve respiratory outcomes.新生儿复苏期间持续通气与标准通气预防死亡及改善呼吸结局的比较
Cochrane Database Syst Rev. 2017 Jul 14;7(7):CD004953. doi: 10.1002/14651858.CD004953.pub3.
6
Delivery room interventions to prevent bronchopulmonary dysplasia in extremely preterm infants.预防极早产儿支气管肺发育不良的产房干预措施。
J Perinatol. 2017 Nov;37(11):1171-1179. doi: 10.1038/jp.2017.74. Epub 2017 Jun 1.
7
Bronchopulmonary Dysplasia: Chronic Lung Disease of Infancy and Long-Term Pulmonary Outcomes.支气管肺发育不良：婴儿期慢性肺病及长期肺部结局
J Clin Med. 2017 Jan 6;6(1):4. doi: 10.3390/jcm6010004.
8
Rayyan-a web and mobile app for systematic reviews.Rayyan——一款用于系统评价的网络和移动应用程序。
Syst Rev. 2016 Dec 5;5(1):210. doi: 10.1186/s13643-016-0384-4.
9
Unraveling the Links Between the Initiation of Ventilation and Brain Injury in Preterm Infants.揭开早产儿通气启动与脑损伤之间的关联。
Front Pediatr. 2015 Nov 10;3:97. doi: 10.3389/fped.2015.00097. eCollection 2015.
10
European Resuscitation Council Guidelines for Resuscitation 2015: Section 7. Resuscitation and support of transition of babies at birth.《2015年欧洲复苏委员会复苏指南：第7节. 出生时新生儿复苏及过渡支持》
Resuscitation. 2015 Oct;95:249-63. doi: 10.1016/j.resuscitation.2015.07.029. Epub 2015 Oct 15.