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氯胺酮与地西泮用于产钳分娩麻醉的比较研究

Ketamine and diazepam as anaesthesia for forceps delivery. A comparative study.

作者信息

Ellingson A, Haram K, Sagen N

出版信息

Acta Anaesthesiol Scand. 1977;21(1):37-40. doi: 10.1111/j.1399-6576.1977.tb01190.x.

Abstract

In a clinically controlled trial in forceps delivery, a comparison was made between the general anaesthesia induced by ketamine and that by a combination of diazepam and N2O. Local anaesthesia was added in the diazepam group for episiotomy and suturation. The indication for operative delivery was in all cases a prolonged second stage of labour. In the katamine group, awareness was noted in four cases out of 13, even if the analgesic effect was found to be good. Four patients showed marked, short-lasting elevation of blood pressure and seven had unpleasant dreams. All thirteen mothers in the diazepam group found the anesthesia effective and the recovery pleasant. The blood pressure was stable. One mother in each group required ventilation with oxygen due to respiratory depression of short duration. Three of the children in the ketamine group and two in the diazepam group had subnormal Apgar score with slight acidosis. This was probably not attributable to the anaesthesia.

摘要

在一项产钳分娩的临床对照试验中,对氯胺酮诱导的全身麻醉与地西泮和笑气联合诱导的全身麻醉进行了比较。地西泮组在会阴切开术和缝合时加用了局部麻醉。所有病例的手术分娩指征均为第二产程延长。在氯胺酮组中,13例中有4例出现术中知晓,尽管镇痛效果良好。4例患者血压明显、短暂升高,7例出现不愉快的梦境。地西泮组的13位母亲均认为麻醉有效且恢复过程舒适。血压稳定。每组各有1位母亲因短时间呼吸抑制需要吸氧通气。氯胺酮组有3名儿童和地西泮组有2名儿童阿氏评分低于正常并有轻度酸中毒。这可能与麻醉无关。

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