Taylor P
MRC Institute of Virology, University of Glasgow, UK.
Comput Appl Biosci. 1988 Nov;4(4):441-3. doi: 10.1093/bioinformatics/4.4.441.
From the measures of evolutionary distance between pairs of sequences in a set, it is possible to infer the genetic tree or trees which best fit these known data. DENDRON is a new program, written in FORTRAN 66, which computes an initial tree from the bottom-up, then searches among increasingly divergent trees for a better fit. As a check on the consistency of the measures, the program tests all triplets for the triangle inequality. DENDRON also calculates a single 'top-down' tree, progressing from the trunk to the twigs, for comparison with the 'bottom-up' trees.
从一组序列对之间的进化距离测量值，可以推断出最符合这些已知数据的一棵或多棵遗传树。DENDRON是一个用FORTRAN 66编写的新程序，它从下往上计算初始树，然后在差异越来越大的树中搜索以找到更好的拟合。作为对测量一致性的检查，该程序会测试所有三元组是否满足三角不等式。DENDRON还会计算一棵从树干到细枝的单一“自上而下”的树，以便与“自下而上”的树进行比较。
