Fatusic Jasenko, Hudic Igor
University Department of Gynecology and Obstetrics, University Clinical Center, Tuzla, Bosnia and Herzegovina.
Med Arch. 2019 Dec;73(6):436-437. doi: 10.5455/medarh.2019.73.436-437.
Gestational trophoblastic desease (GTD) is disease typical for reproductive period of women and is extremly rare in postmenopausal period of woman's life.
To present a rare case of mollar pregnancy in 57 years of age postmenopausal woman.
A multiparous woman aged 57 years, and two yars after last menstrual bleeding, was admitted at Clinic, due to hyperplastic endometrium findings and moderate prolonged postmenopausal uterine bleeding. Due to clinical simptoms we performed diagnostic exploratice curettage. During that intervention heavy bleeding was developed resulting in spontaneous expulsion of tumorous mass wich macroscopic looked as a mollar tissue. Imediatelly after intervention level of β HCG was 193,057mlU/mL. Due to very high level of β HCG patient was taken to laparotomy and during the surgery dicision was made to perform total abdominal hysterectomy with bilateral adnexectomy. Eight day after surgery patient was discharged from Clinic in good condition. Hystopathological examination of material obtained by explorative curettage and uterus showed complete mollar pregnancy. Controlled level of β HCG was 1,996 mlU/mL fifth day after surgery.
Although molar pregnancy in postmenopausal period of woman's life is very rare disorder, because of potentialy heavy complications it is very important to recognise this disorder at time, to prevent delay of treatment.
妊娠滋养细胞疾病(GTD)是女性生育期特有的疾病,在女性绝经后期极为罕见。
报告一例57岁绝经后妇女葡萄胎妊娠的罕见病例。
一名57岁经产妇,末次月经出血两年后,因增生期子宫内膜表现及绝经后子宫中度延长性出血入住诊所。由于临床症状,我们进行了诊断性刮宫。在该操作过程中出现大出血,导致肿瘤性肿块自然排出,肉眼观察为葡萄胎组织。干预后立即检测β-HCG水平为193,057mlU/mL。由于β-HCG水平极高,患者接受了剖腹手术,术中决定行全腹子宫切除术及双侧附件切除术。术后八天患者康复出院。对诊断性刮宫获取的组织及子宫进行的组织病理学检查显示为完全性葡萄胎妊娠。术后第五天检测β-HCG控制水平为1,996mlU/mL。
尽管绝经后妇女葡萄胎妊娠是一种非常罕见的疾病,但由于可能出现严重并发症,及时识别该疾病以防止治疗延误非常重要。