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绝经后妇女完全性葡萄胎——病例报告

Complete Molar Pregnancy in Posmenopausal Woman-a Case Report.

作者信息

Fatusic Jasenko, Hudic Igor

机构信息

University Department of Gynecology and Obstetrics, University Clinical Center, Tuzla, Bosnia and Herzegovina.

出版信息

Med Arch. 2019 Dec;73(6):436-437. doi: 10.5455/medarh.2019.73.436-437.

DOI:10.5455/medarh.2019.73.436-437
PMID:32082016
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7007621/
Abstract

INTRODUCTION

Gestational trophoblastic desease (GTD) is disease typical for reproductive period of women and is extremly rare in postmenopausal period of woman's life.

AIM

To present a rare case of mollar pregnancy in 57 years of age postmenopausal woman.

CASE REPORT

A multiparous woman aged 57 years, and two yars after last menstrual bleeding, was admitted at Clinic, due to hyperplastic endometrium findings and moderate prolonged postmenopausal uterine bleeding. Due to clinical simptoms we performed diagnostic exploratice curettage. During that intervention heavy bleeding was developed resulting in spontaneous expulsion of tumorous mass wich macroscopic looked as a mollar tissue. Imediatelly after intervention level of β HCG was 193,057mlU/mL. Due to very high level of β HCG patient was taken to laparotomy and during the surgery dicision was made to perform total abdominal hysterectomy with bilateral adnexectomy. Eight day after surgery patient was discharged from Clinic in good condition. Hystopathological examination of material obtained by explorative curettage and uterus showed complete mollar pregnancy. Controlled level of β HCG was 1,996 mlU/mL fifth day after surgery.

CONCLUSION

Although molar pregnancy in postmenopausal period of woman's life is very rare disorder, because of potentialy heavy complications it is very important to recognise this disorder at time, to prevent delay of treatment.

摘要

引言

妊娠滋养细胞疾病(GTD)是女性生育期特有的疾病,在女性绝经后期极为罕见。

目的

报告一例57岁绝经后妇女葡萄胎妊娠的罕见病例。

病例报告

一名57岁经产妇,末次月经出血两年后,因增生期子宫内膜表现及绝经后子宫中度延长性出血入住诊所。由于临床症状,我们进行了诊断性刮宫。在该操作过程中出现大出血,导致肿瘤性肿块自然排出,肉眼观察为葡萄胎组织。干预后立即检测β-HCG水平为193,057mlU/mL。由于β-HCG水平极高,患者接受了剖腹手术,术中决定行全腹子宫切除术及双侧附件切除术。术后八天患者康复出院。对诊断性刮宫获取的组织及子宫进行的组织病理学检查显示为完全性葡萄胎妊娠。术后第五天检测β-HCG控制水平为1,996mlU/mL。

结论

尽管绝经后妇女葡萄胎妊娠是一种非常罕见的疾病,但由于可能出现严重并发症,及时识别该疾病以防止治疗延误非常重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/252f/7007621/240101697d34/medarch-73-436-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/252f/7007621/fc8169254fc2/medarch-73-436-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/252f/7007621/240101697d34/medarch-73-436-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/252f/7007621/fc8169254fc2/medarch-73-436-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/252f/7007621/240101697d34/medarch-73-436-g002.jpg

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本文引用的文献

1
Gestational trophoblastic disease I: epidemiology, pathology, clinical presentation and diagnosis of gestational trophoblastic disease, and management of hydatidiform mole.妊娠滋养细胞疾病 I:流行病学、病理学、临床表现和诊断、葡萄胎的处理。
Am J Obstet Gynecol. 2010 Dec;203(6):531-9. doi: 10.1016/j.ajog.2010.06.073. Epub 2010 Aug 21.
2
Routine pre-evacuation ultrasound diagnosis of hydatidiform mole: experience of more than 1000 cases from a regional referral center.葡萄胎清宫前的常规超声诊断:来自地区转诊中心1000多例病例的经验
Ultrasound Obstet Gynecol. 2006 Jan;27(1):56-60. doi: 10.1002/uog.2592.
3
Risk of recurrent hydatidiform mole and subsequent pregnancy outcome following complete or partial hydatidiform molar pregnancy.
完全性或部分性葡萄胎妊娠后复发性葡萄胎的风险及后续妊娠结局
BJOG. 2003 Jan;110(1):22-6.
4
Molar pregnancy in a 60-year-old woman.一名60岁女性的葡萄胎妊娠。
Int J Gynaecol Obstet. 1997 Jan;56(1):53-5. doi: 10.1016/s0020-7292(96)02781-6.
5
Malignant potential of gestational trophoblastic disease at the extreme ages of reproductive life.生殖生命极端年龄阶段妊娠滋养细胞疾病的恶性潜能。
Obstet Gynecol. 1984 Sep;64(3):395-9.
6
Epidemiology of hydatidiform mole during early gestation.妊娠早期葡萄胎的流行病学
Am J Obstet Gynecol. 1986 Apr;154(4):906-9. doi: 10.1016/0002-9378(86)90482-5.
7
Gestational trophoblastic disease in women aged 50 or more.
Gynecol Oncol. 1985 Jan;20(1):53-61. doi: 10.1016/0090-8258(85)90124-6.