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一名52岁绝经后妇女的完全性葡萄胎:病例报告及文献复习

Complete hydatidiform mole in a 52-year-old postmenopausal woman: A case report and literature review.

作者信息

Wang Qin, Dong Hui

机构信息

Sichuan Provincial Center for Gynecology and Breast Diseases (Gynecology), PR China.

Department of Pathology, Affiliated Hospital of Southwest Medical University, Luzhou 646000, Sichuan, PR China.

出版信息

Case Rep Womens Health. 2021 Jun 19;31:e00338. doi: 10.1016/j.crwh.2021.e00338. eCollection 2021 Jul.

Abstract

Benign gestational trophoblastic disease generally occurs in women of reproductive age and is extremely rare in postmenopausal women. Here, the authors describe a case of complete hydatidiform mole in a 52-year-old postmenopausal woman with a history of lower abdominal bloating and vaginal bleeding. The paper summarizes the clinical manifestations, physiopathology, diagnosis, and treatment options for gestational trophoblastic disease in postmenopausal women. This study highlights that gestational trophoblastic disease can occur in postmenopausal women and that it is important to include it in the differential diagnosis of postmenopausal bleeding, to prevent delay in treatment.

摘要

良性妊娠滋养细胞疾病一般发生于育龄期女性,在绝经后女性中极为罕见。在此,作者描述了一例52岁绝经后女性患完全性葡萄胎的病例,该患者有下腹胀和阴道出血病史。本文总结了绝经后女性妊娠滋养细胞疾病的临床表现、病理生理学、诊断及治疗选择。这项研究强调妊娠滋养细胞疾病可发生于绝经后女性,将其纳入绝经后出血的鉴别诊断中很重要,以防延误治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a2fc/8255813/d9a50a4ff180/gr1.jpg

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本文引用的文献

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Understanding and management of gestational trophoblastic disease.妊娠滋养细胞疾病的认识与管理
F1000Res. 2019 Apr 10;8. doi: 10.12688/f1000research.14953.1. eCollection 2019.
4
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Indian J Surg Oncol. 2017 Jun;8(2):185-187. doi: 10.1007/s13193-016-0603-4. Epub 2016 Dec 19.
5
Insights into dovetailing GTD and Cancers.对将GTD与癌症相结合的见解。
Crit Rev Oncol Hematol. 2017 Jun;114:77-90. doi: 10.1016/j.critrevonc.2017.04.001. Epub 2017 Apr 7.
6
Complete molar pregnancy in postmenopausal women.绝经后妇女的完全性葡萄胎
J Midlife Health. 2016 Apr-Jun;7(2):91-3. doi: 10.4103/0976-7800.185328.
9
Molar pregnancy in postmenopausal women: a rare phenomenon.绝经后妇女的葡萄胎:一种罕见现象。
BMJ Case Rep. 2012 Sep 11;2012:bcr2012006213. doi: 10.1136/bcr-2012-006213.
10
Bilateral adnexal torsion due to postmenopausal hydatidiform mole.
J Obstet Gynaecol Res. 2011 Apr;37(4):359-62. doi: 10.1111/j.1447-0756.2010.01347.x. Epub 2011 Feb 23.

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