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萨拉热窝斯韦特洛斯特眼科诊所糖尿病视网膜病变的流行病学:一项为期两年的回顾性单中心研究。

Epidemiology of Diabetic Retinopathy at Eye Clinic Svjetlost Sarajevo: Two Years Retrospective Single Center Study.

作者信息

Pidro Ajla, Ahmedbegovic-Pjano Melisa, Grisevic Senad, Sofic-Drino Vernesa, Gabric Kresimir, Biscevic Alma

机构信息

Eye Clinic Svjetlost Sarajevo, Sarajevo, Bosnia and Herzegovina.

University Eye Clinic Svjetlost Zagreb, Zagreb, Croatia.

出版信息

Mater Sociomed. 2019 Dec;31(4):290-293. doi: 10.5455/msm.2019.31.290-293.

Abstract

INTRODUCTION

Diabetic retinopathy (DR) is an important cause of blindness, and occurs as a result of long-term accumulated damage to the small blood vessels in the retina. 2.6% of global blindness can be attributed to diabetes. Disease severity was most often classified by the Early Treatment Diabetic Retinopathy Study (ETDRS) classification for DR severity. Patients are usually categorized based on the severity of DR as having mild nonproliferative diabetic retinopathy (NPDR), moderate NPDR, severe NPDR, or proliferative diabetic retinopathy (PDR).

AIM

To evaluate DR status among patients at Eye Clinic Svjetlost Sarajevo , both, type 1 and type 2 DM patients who presented in our clinic at 2 years period - from June 2016 to June 2018. This is single center study.

METHODS

Retrospective analysis of 753 diabetic patients that came for the first check up in our institution during those two years, 363 patients were male and 390 were female. Patients were divided in 3 groups (based on DR changes): a) No changes, b) Nonproliferative DR (with and without Diabetic macular edema-DME), c) Prolipherative DR (with and without DME + Advanced PDR).

RESULTS

There were 35% of patients with no ocular changes, 41.2% had NPDR and 24% had PDR. Prevalence of DR in our study was 65.32%. Distribution of NPDR was 66.27%, and PDR was 33.73%. DME was present in 33.70% cases. In NPDR, DME was presented in 51% of the cases, while in PDR was presented in 49% of the cases. In state of advanced PDR, PDR was presented in 30.52% cases, tractional detachment and haemophtalmus in 50.20% of cases and neovascular glaucoma in 19.28%. Sixty-three patients ended up with vitroretinal surgery (8.4%) while in other studies that number is up to 3%. Out of that number 9 patients were patient with virgin eyes (14.28%). Neovascular glaucoma occurred in 19.28% of diabetics with proliferative retinopathy and 4.60% in all of diabetics.

CONCLUSION

Diabetic retinopathy status of patients presenting at Eye clinic Svjetlost Sarajevo, Bosnia and Herzegovina is quite poor. There is a big need for early DR screening measures, good prevention and management of DR risk factors. Adequate and ON TIME management of DM and its vision threatening complications is of major importance.

摘要

引言

糖尿病视网膜病变(DR)是导致失明的重要原因,是视网膜小血管长期累积损伤的结果。全球2.6%的失明可归因于糖尿病。疾病严重程度通常根据糖尿病视网膜病变早期治疗研究(ETDRS)对DR严重程度的分类来划分。患者通常根据DR的严重程度分为轻度非增殖性糖尿病视网膜病变(NPDR)、中度NPDR、重度NPDR或增殖性糖尿病视网膜病变(PDR)。

目的

评估萨拉热窝斯韦特洛斯特眼科诊所1型和2型糖尿病患者在2016年6月至2018年6月这两年期间的DR状况。这是一项单中心研究。

方法

对这两年期间首次到本机构进行检查的753例糖尿病患者进行回顾性分析,其中男性363例,女性390例。患者分为3组(根据DR变化):a)无变化,b)非增殖性DR(伴有或不伴有糖尿病性黄斑水肿-DME),c)增殖性DR(伴有或不伴有DME+晚期PDR)。

结果

35%的患者无眼部变化,41.2%患有NPDR,24%患有PDR。本研究中DR的患病率为65.32%。NPDR的分布为66.27%,PDR为33.73%。33.70%的病例存在DME。在NPDR中,51%的病例存在DME,而在PDR中,49%的病例存在DME。在晚期PDR状态下,30.52%的病例存在PDR,50.20%的病例存在牵拉性视网膜脱离和玻璃体积血,19.28%的病例存在新生血管性青光眼。63例患者最终接受了玻璃体视网膜手术(8.4%),而在其他研究中这一数字高达3%。其中9例患者为初诊患者(14.28%)。增殖性视网膜病变的糖尿病患者中19.28%发生新生血管性青光眼,所有糖尿病患者中4.60%发生新生血管性青光眼。

结论

波斯尼亚和黑塞哥维那萨拉热窝斯韦特洛斯特眼科诊所患者的糖尿病视网膜病变状况相当糟糕。迫切需要早期DR筛查措施、对DR危险因素进行良好的预防和管理。对糖尿病及其威胁视力的并发症进行充分且及时的管理至关重要。

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