Kahloun R, Jelliti B, Zaouali S, Attia S, Ben Yahia S, Resnikoff S, Khairallah M
1] Department of Ophthalmology, Fattouma Bourguiba University Hospital, Monastir, Tunisia [2] Faculty of Medicine, University of Monastir, Monastir, Tunisia.
International Health and Development, Geneva, Switzerland.
Eye (Lond). 2014 Aug;28(8):986-91. doi: 10.1038/eye.2014.131. Epub 2014 Jun 13.
To investigate the prevalence and causes of blindness and partial sight among a population of Tunisian diabetic patients.
A cross-sectional study of 2320 randomly identified patients with diabetes mellitus. Patient's characteristics as well as data from the last ophthalmic examination were reviewed.
Of all patients examined, 60.2% were females and 39.8% were males. Mean age of patients was 54.5 years. Mean duration of diabetes was 7.6 years. Diabetic retinopathy (DR) was recorded in 26.3% of patients, and was proliferative in 3.4% of patients. The prevalence of visual impairment was 22.2%, with 4.4% patients legally blind and 17.8% partially sighted. Visual impairment was significantly associated with age ≥60 years (P<0.001), duration of diabetes >10 years (P<0.001), body mass index >25 (P=0.014), hypertension (P<0.001), heart disease (P<0.001), peripheral neuropathy (P=0.03), vegetative neuropathy (P=0.002), macroalbuminuria (P<0.001), cataract (P<0.001), DR (P<0.001), diabetic macular edema (P<0.001), open angle glaucoma (P<0.001), intravitreal hemorrhage (P<0.001), rubeosis iridis (P<0.001), neovascular glaucoma (P<0.001), and tractional retinal detachment (P<0.001).
The current report is the largest study of DR in North African region. It provides a baseline data against which future progress can be assessed. Screening and treatment can greatly reduce the incidence of visual impairment due to diabetes.
调查突尼斯糖尿病患者群体中失明和视力部分丧失的患病率及病因。
对2320例随机选取的糖尿病患者进行横断面研究。回顾了患者的特征以及上次眼科检查的数据。
在所有接受检查的患者中,60.2%为女性,39.8%为男性。患者的平均年龄为54.5岁。糖尿病的平均病程为7.6年。26.3%的患者记录有糖尿病视网膜病变(DR),其中3.4%为增殖性病变。视力损害的患病率为22.2%,4.4%的患者法定失明,17.8%的患者视力部分丧失。视力损害与年龄≥60岁(P<0.001)、糖尿病病程>10年(P<0.001)、体重指数>25(P=0.014)、高血压(P<0.001)、心脏病(P<0.001)、周围神经病变(P=0.03)、自主神经病变(P=0.002)、大量蛋白尿(P<0.001)、白内障(P<0.001)、DR(P<0.001)、糖尿病性黄斑水肿(P<0.001)、开角型青光眼(P<0.001)、玻璃体积血(P<0.001)、虹膜红变(P<0.001)、新生血管性青光眼(P<0.001)和牵拉性视网膜脱离(P<0.001)显著相关。
本报告是北非地区关于DR的最大规模研究。它提供了一个可据此评估未来进展的基线数据。筛查和治疗可大大降低糖尿病所致视力损害的发生率。