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2
The Activation and Function of Autophagy in Alcoholic Liver Disease.自噬在酒精性肝病中的激活与功能
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Ethanol-induced hepatic autophagy: Friend or foe?乙醇诱导的肝脏自噬：是友还是敌？
World J Hepatol. 2015 May 28;7(9):1154-6. doi: 10.4254/wjh.v7.i9.1154.
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Quercetin alleviates ethanol-induced liver steatosis associated with improvement of lipophagy.槲皮素通过改善脂噬缓解乙醇诱导的肝脂肪变性。
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Editorial: Emerging mechanistic insights of selective and Nonselective Autophagy in liver and gut diseases and their treatment strategies in the era of COVID-19.社论：肝脏和肠道疾病中选择性和非选择性自噬的新机制见解及其在 COVID-19 时代的治疗策略
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Ethanol withdrawal mitigates fatty liver by normalizing lipid catabolism.乙醇戒断通过使脂质分解代谢正常化来减轻脂肪肝。
Am J Physiol Gastrointest Liver Physiol. 2019 Apr 1;316(4):G509-G518. doi: 10.1152/ajpgi.00376.2018. Epub 2019 Feb 4.
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Biomolecules. 2015 Oct 16;5(4):2659-74. doi: 10.3390/biom5042659.
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Lipophagy in nonliver tissues and some related diseases: Pathogenic and therapeutic implications.非肝脏组织中的脂噬作用及其相关疾病：发病机制和治疗意义。
J Cell Physiol. 2019 Jun;234(6):7938-7947. doi: 10.1002/jcp.27988. Epub 2018 Dec 10.
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Methionine and S-adenosylmethionine levels are critical regulators of PP2A activity modulating lipophagy during steatosis.蛋氨酸和S-腺苷甲硫氨酸水平是PP2A活性的关键调节因子，在脂肪变性过程中调节脂质自噬。
J Hepatol. 2016 Feb;64(2):409-418. doi: 10.1016/j.jhep.2015.08.037. Epub 2015 Sep 21.
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TFE3 Alleviates Hepatic Steatosis through Autophagy-Induced Lipophagy and PGC1α-Mediated Fatty Acid β-Oxidation.TFE3 通过自噬诱导的脂质吞噬和 PGC1α 介导的脂肪酸 β-氧化减轻肝脂肪变性。
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Remnant cholesterol is associated with hip BMD and low bone mass in young and middle-aged men: a cross-sectional study.残胆固醇与年轻和中年男性髋部 BMD 和低骨量相关：一项横断面研究。
J Endocrinol Invest. 2024 Jul;47(7):1657-1665. doi: 10.1007/s40618-023-02279-x. Epub 2024 Jan 6.

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An update of SGLT1 and SGLT2 inhibitors in early phase diabetes-type 2 clinical trials.在早期 2 型糖尿病临床试验中 SGLT1 和 SGLT2 抑制剂的更新。
Expert Opin Investig Drugs. 2019 Sep;28(9):811-820. doi: 10.1080/13543784.2019.1655539. Epub 2019 Aug 22.
2
Nrf2 signaling and autophagy are complementary in protecting lipopolysaccharide/d-galactosamine-induced acute liver injury by licochalcone A.姜黄素 A 通过 Nrf2 信号通路和自噬对脂多糖/半乳糖胺诱导的急性肝损伤起保护作用，二者具有协同作用。
Cell Death Dis. 2019 Apr 5;10(4):313. doi: 10.1038/s41419-019-1543-z.
3
Ethanol-Induced Mitochondrial Damage in Sertoli Cells is Associated with Parkin Overexpression and Activation of Mitophagy.乙醇诱导的支持细胞中线粒体损伤与 Parkin 过表达和自噬激活有关。
Cells. 2019 Mar 25;8(3):283. doi: 10.3390/cells8030283.
4
Curcumin confers hepatoprotection against AFB-induced toxicity via activating autophagy and ameliorating inflammation involving Nrf2/HO-1 signaling pathway.姜黄素通过激活自噬和改善涉及Nrf2/HO-1信号通路的炎症，对黄曲霉毒素诱导的毒性发挥肝脏保护作用。
Mol Biol Rep. 2018 Dec;45(6):1775-1785. doi: 10.1007/s11033-018-4323-4. Epub 2018 Aug 24.
5
Author Correction: Small-molecule TFEB pathway agonists that ameliorate metabolic syndrome in mice and extend C. elegans lifespan.作者更正：改善小鼠代谢综合征并延长秀丽隐杆线虫寿命的小分子TFEB通路激动剂。
Nat Commun. 2018 May 21;9(1):2050. doi: 10.1038/s41467-018-04519-8.
6
Molecular definitions of autophagy and related processes.自噬及相关过程的分子定义。
EMBO J. 2017 Jul 3;36(13):1811-1836. doi: 10.15252/embj.201796697. Epub 2017 Jun 8.
7
Upregulated Autophagy in Sertoli Cells of Ethanol-Treated Rats Is Associated with Induction of Inducible Nitric Oxide Synthase (iNOS), Androgen Receptor Suppression and Germ Cell Apoptosis.乙醇处理大鼠睾丸支持细胞中自噬上调与诱导型一氧化氮合酶（iNOS）的诱导、雄激素受体抑制及生殖细胞凋亡有关。
Int J Mol Sci. 2017 May 15;18(5):1061. doi: 10.3390/ijms18051061.
8
Viral rewiring of cellular lipid metabolism to create membranous replication compartments.病毒对细胞脂质代谢进行重编程以创建膜性复制区室。
Curr Opin Cell Biol. 2017 Aug;47:24-33. doi: 10.1016/j.ceb.2017.02.005. Epub 2017 Feb 24.
9
Transcription factor EB: from master coordinator of lysosomal pathways to candidate therapeutic target in degenerative storage diseases.转录因子EB：从溶酶体途径的主要协调者到退行性贮积病的候选治疗靶点
Ann N Y Acad Sci. 2016 May;1371(1):3-14. doi: 10.1111/nyas.13131.
10
Triggering of Parkin Mitochondrial Translocation in Mitophagy: Implications for Liver Diseases.线粒体自噬中帕金蛋白线粒体易位的触发：对肝脏疾病的影响
Front Pharmacol. 2016 Apr 29;7:100. doi: 10.3389/fphar.2016.00100. eCollection 2016.

Editorial: Autophagy and Related Transcription Factors in Liver and Gut Diseases.

作者信息

Eid Nabil, Menon Manoj B, Thomes Paul, Zeng Tao, Raimundo Nuno, Fernandez-Checa Jose C, Wang Lin, Ito Yuko, Otsuki Yoshinori, Adeghate Ernest

机构信息

Department of Anatomy, College of Medicine and Health Sciences, United Arab Emirates University, Al Ain, United Arab Emirates.

Kusuma School of Biological Sciences, Indian Institute of Technology Delhi, New Delhi, India.

出版信息

Front Pharmacol. 2020 Jan 30;10:1610. doi: 10.3389/fphar.2019.01610. eCollection 2019.

DOI:10.3389/fphar.2019.01610
PMID:32082148
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7002321/
Abstract
摘要