Department of Nutrition and Dietetics, Faculty of Health Sciences, Beirut Arab University, Beirut, Lebanon.
Front Endocrinol (Lausanne). 2020 Jan 30;11:22. doi: 10.3389/fendo.2020.00022. eCollection 2020.
Understanding the condition that describes the coexistence of obesity and sarcopenia, termed sarcopenic obesity (SO), is becoming a scientific and clinical priority. In this study, we aimed to assess the prevalence of SO in treatment-seeking adults with obesity and investigate any potential association between SO and a sedentary lifestyle, expressed in terms of daily steps. In this cross-sectional, prospective observational study, body composition and daily steps measurements were obtained using a segmental body composition analyser (Tanita BC-418) and an Omron HJ-320 pedometer, respectively, in 111 adults of both genders with obesity (body mass index; BMI ≥ 30 kg/m), referred to the Outpatient Clinic in the Department of Nutrition and Dietetics at Beirut Arab University (BAU) in Lebanon. The participants were then categorized according to the presence of absence of SO, defined as an appendicular lean mass divided by body weight (ALM/weight) × 100%) of less than 23.40 and 29.60 in females and males, respectively. Fifty-five of the 111 participants with obesity, with a mean age of 39.62 ± 16.55 years and a mean BMI of 38.05 ± 5.33 kg/m met the criteria for SO and displayed a significantly higher prevalence of inactivity (<5,000 daily steps), i.e., nearly double (54.5% vs. 32.1%; = 0.017) and they had a lower mean number of daily steps than those in the group without SO (5,279 ± 2,641 vs. 6,732 ± 2,989; = 0.008). Linear regression analysis showed that SO is associated with a lower number of daily steps by 1,421 (β = -1421.4; -2508.9, -333.9; = 0.011) after adjusting for age, gender employment and the presence of cardiometabolic disease. Sarcopenic obesity affects nearly 50% of treatment-seeking adults with obesity. Moreover, it seems to be associated with a lower number of daily steps and a sedentary lifestyle. Future studies are needed to clarify whether this may influence clinical outcomes. If this is shown to be the case, weight management programmes should incorporate additional physical activity strategies in this population.
了解肥胖和肌少症共存的状况，即肌少症性肥胖（SO），正成为科学和临床的重点。本研究旨在评估寻求肥胖治疗的成年人中 SO 的患病率，并研究 SO 与久坐生活方式之间的潜在关联，用日常步数来表示。
在这项横断面、前瞻性观察研究中，使用 Tanita BC-418 分段式身体成分分析仪和 Omron HJ-320 计步器分别测量了 111 名男女肥胖患者（体重指数；BMI≥30kg/m）的身体成分和日常步数，这些患者被转诊到黎巴嫩贝鲁特阿拉伯大学（BAU）营养与饮食学部的门诊。然后，根据是否存在 SO 将参与者分为两组，SO 定义为四肢瘦体重（ALM）除以体重（ALM/体重）×100%）女性<23.40，男性<29.60。
111 名肥胖患者中有 55 名符合 SO 标准，平均年龄为 39.62±16.55 岁，平均 BMI 为 38.05±5.33kg/m，他们的非活跃率（<5000 步/天）明显更高，即近两倍（54.5% vs. 32.1%；=0.017），他们的日常步数也明显低于无 SO 组（5279±2641 步 vs. 6732±2989 步；=0.008）。线性回归分析表明，在校正年龄、性别、就业和心血管代谢疾病的存在后，SO 与每日步数减少 1421 步相关（β=-1421.4；-2508.9，-333.9；=0.011）。
肌少症性肥胖影响了近 50%寻求肥胖治疗的成年人。此外，它似乎与日常步数减少和久坐的生活方式有关。需要进一步的研究来阐明这是否会影响临床结果。如果情况确实如此，那么体重管理计划应该在这一人群中纳入额外的体育活动策略。
