Tannir Hana, Itani Leila, Kreidieh Dima, El Masri Dana, El Ghoch Marwan
Department of Nutrition and Dietetics, Faculty of Health Sciences, Beirut Arab University, P.O. Box 11-5020 Riad El Solh, Beirut 11072809, Lebanon.
Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, 41125 Modena, Italy.
Clin Pract. 2022 Feb 17;12(1):106-112. doi: 10.3390/clinpract12010014.
Little remains known regarding the impact of weight loss on sarcopenic obesity (SO), and for this reason we aimed to assess the relationship between the two during a weight management program. Body composition was measured at baseline and six-month follow-up using the Tanita BC-418, and step measurements were obtained daily over a period of six months using an Omron HJ-320 pedometer, in 41 adults of both genders with obesity. The participants were then categorized according to the presence or absence of SO. After a significant weight loss, an improvement in the appendicular skeletal mass (ASM) to weight ratio (24.5 ± 3.5 vs. 26.2 ± 3.6, < 0.01), indicated a decrease in the prevalence of SO by 12.2%. Moreover, these findings were confirmed by logistic regression analysis revealing a significant WL% ≥ 5% combined with an active lifestyle (i.e., ≥8000 steps/day), decreased the risk of SO by 91% (OR = 0.09; 95% CI: 0.02-0.56), after adjusting for age and gender. In conclusion, in a weight management setting, a personalized program for individuals with SO that incorporates new strategies in terms of weight loss and physical activity targets may be adopted to improve the sarcopenia-related index and reduce the prevalence of SO in this population.
关于体重减轻对肌少症性肥胖（SO）的影响，目前所知甚少。因此，我们旨在评估在体重管理计划期间两者之间的关系。使用Tanita BC - 418在基线和六个月随访时测量身体成分，并使用欧姆龙HJ - 320计步器在六个月的时间里每天记录步数，研究对象为41名患有肥胖症的成年男女。然后根据是否存在SO对参与者进行分类。在显著减重后，四肢骨骼肌质量（ASM）与体重之比有所改善（24.5±3.5 vs. 26.2±3.6，<0.01），表明SO的患病率降低了12.2%。此外，逻辑回归分析证实了这些发现，结果显示在调整年龄和性别后，体重减轻百分比（WL%）≥5%且结合积极的生活方式（即每天步数≥8000步）可使SO风险降低91%（OR = 0.09；95%CI：0.02 - 0.56）。总之，在体重管理环境中，对于患有SO的个体，可以采用个性化方案，该方案在体重减轻和身体活动目标方面纳入新策略，以改善与肌少症相关的指标并降低该人群中SO的患病率。
