• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

巨大皮肤角中的疣状癌:一例报告及文献综述

Verrucous Carcinoma in a Giant Cutaneous Horn: A Case Report and Literature Review.

作者信息

Shahi Sudha, Bhandari Tika Ram, Pantha Tridip

机构信息

Otorhinolaryngology Head and Neck Surgery, National Academy of Medical Sciences, Bir Hospital, Kathmandu, Nepal.

General Surgery, People's Dental College and Hospital, Kathmandu, Nepal.

出版信息

Case Rep Otolaryngol. 2020 Jan 31;2020:7134789. doi: 10.1155/2020/7134789. eCollection 2020.

DOI:10.1155/2020/7134789
PMID:32082671
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7013305/
Abstract

BACKGROUND

A cutaneous horn is a common clinical entity which usually presents as a cutaneous lesion. Because of its subtle nature, patients usually tend to present late unless the lesion is big or complications develop. Because of its resemblance to animal horn, it has been given the term "horn." Cutaneous horn seems to have a remarkable history. Though cutaneous horn is benign most of the times, chances of malignancy (20-25%) should be kept in mind. Old age, giant cutaneous horn carries more chances of transformation into malignancy like in our case. Thus, early diagnosis and treatment is required in all cases. . We report a case of a 74-year-old farmer with a cutaneous projection measuring ∼8 × 5 × 3 cm over the medial surface of the right pinna for 1 year. It started as a small projection which was progressively enlarging. The primary reason behind him presenting to us was cosmetic reason since it resembled an animal horn. The projection was not associated with pain or similar lesions anywhere else in body. Understanding the malignancy risks and the cosmetic benefits, he was planned for excision biopsy of the horn. He had no systemic signs of malignancy. Histopathological reports were consistent with malignancy.

CONCLUSIONS

Cutaneous horns are usually benign lesions and mostly found in the head and neck region. Because of the chances of malignancy, cutaneous horns should undergo surgical removal and biopsy for early and definitive diagnosis and management.

摘要

背景

皮肤角是一种常见的临床病症,通常表现为皮肤病变。由于其性质隐匿,除非病变较大或出现并发症,否则患者通常就诊较晚。因其形似动物的角,故而得名“角”。皮肤角似乎有着显著的病史。尽管皮肤角多数情况下是良性的,但应牢记其有恶变的可能(20% - 25%)。老年患者、巨大皮肤角如我们病例中的情况,发生恶变的几率更高。因此,所有病例均需早期诊断和治疗。我们报告一例74岁农民,其右耳廓内侧面有一个大小约为8×5×3厘米的皮肤突起,已存在1年。起初是一个小突起,随后逐渐增大。他前来就诊的主要原因是外观问题,因为它看起来像动物的角。该突起不伴有疼痛,身体其他部位也无类似病变。考虑到恶变风险和外观改善,计划对其进行角的切除活检。他没有恶性肿瘤的全身症状。组织病理学报告显示为恶性。

结论

皮肤角通常是良性病变,大多见于头颈部区域。鉴于有恶变的可能,皮肤角应接受手术切除并进行活检,以便早期明确诊断和治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a6f/7013305/6c2fffdf5dc4/CRIOT2020-7134789.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a6f/7013305/6c2fffdf5dc4/CRIOT2020-7134789.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a6f/7013305/6c2fffdf5dc4/CRIOT2020-7134789.001.jpg

相似文献

1
Verrucous Carcinoma in a Giant Cutaneous Horn: A Case Report and Literature Review.巨大皮肤角中的疣状癌:一例报告及文献综述
Case Rep Otolaryngol. 2020 Jan 31;2020:7134789. doi: 10.1155/2020/7134789. eCollection 2020.
2
Giant Cutaneous Horn: Is It a Tip of An Iceberg? Two Case Reports and a Review of Literature.巨大皮肤角:它是冰山一角吗?两例病例报告及文献综述
Indian J Otolaryngol Head Neck Surg. 2022 Dec;74(Suppl 3):5432-5435. doi: 10.1007/s12070-021-02719-1. Epub 2021 Jul 6.
3
A Giant Cutaneous Horn Projecting from Verrucous Carcinoma of Buccal Mucosa: A Rare Case Report.一例源自颊黏膜疣状癌的巨大皮肤角:罕见病例报告
J Clin Diagn Res. 2017 Mar;11(3):ZD04-ZD05. doi: 10.7860/JCDR/2017/24657.9361. Epub 2017 Mar 1.
4
Cutaneous horn: A mask to underlying malignancy.皮肤角:潜在恶性肿瘤的一种表象。
J Oral Maxillofac Pathol. 2018 Jan;22(Suppl 1):S87-S90. doi: 10.4103/jomfp.JOMFP_156_17.
5
Breast horn; A rare case presentation.
Ann Med Surg (Lond). 2022 Apr 8;77:103598. doi: 10.1016/j.amsu.2022.103598. eCollection 2022 May.
6
A rapidly growing giant cutaneous horn on the chest.胸部一个迅速生长的巨大皮肤角。
J Dermatol Case Rep. 2015 Dec 31;9(4):113-5. doi: 10.3315/jdcr.2015.1217.
7
Cutaneous Horn: A Masquerade to Underlying Keratotic Basal Cell Carcinoma.
Cureus. 2022 Dec 12;14(12):e32427. doi: 10.7759/cureus.32427. eCollection 2022 Dec.
8
A Curious Case of Cutaneous Horn.
Cureus. 2020 Sep 5;12(9):e10253. doi: 10.7759/cureus.10253.
9
Cornu Cutaneum: Case Reports of Patients With a Cutaneous Horn Associated With Either a Verruca Vulgaris or an Inverted Follicular Keratosis and a Review of the Etiologies of Cutaneous Horns.皮角:伴有寻常疣或倒置性毛囊角化病的皮角患者病例报告及皮角病因综述
Cureus. 2023 Oct 9;15(10):e46747. doi: 10.7759/cureus.46747. eCollection 2023 Oct.
10
Well-Differentiated Squamous Cell Carcinoma Presenting as Branched Eyelid Cutaneous Horn: A Case Report with Review of Literature.以分支状眼睑皮肤角表现的高分化鳞状细胞癌:一例报告并文献复习
Indian Dermatol Online J. 2017 Jul-Aug;8(4):261-263. doi: 10.4103/idoj.IDOJ_327_16.

引用本文的文献

1
Cornu Cutaneum: Case Reports of Patients With a Cutaneous Horn Associated With Either a Verruca Vulgaris or an Inverted Follicular Keratosis and a Review of the Etiologies of Cutaneous Horns.皮角:伴有寻常疣或倒置性毛囊角化病的皮角患者病例报告及皮角病因综述
Cureus. 2023 Oct 9;15(10):e46747. doi: 10.7759/cureus.46747. eCollection 2023 Oct.
2
Unraveling the Enigma: A Report on a Rare Case of Cutaneous Horn, an Extraordinary Dermatological Occurrence.揭开谜团:一例罕见的皮肤角病例报告,一种非凡的皮肤病学现象。
Cureus. 2023 Jul 17;15(7):e41987. doi: 10.7759/cureus.41987. eCollection 2023 Jul.
3
Giant Cutaneous Horn: Is It a Tip of An Iceberg? Two Case Reports and a Review of Literature.

本文引用的文献

1
Observations on Certain Horny Excrescences of the Human Body: From the Philosophical Transactions of the Royal Society of London.关于人体某些角质赘生物的观察:源自伦敦皇家学会《哲学学报》
Med Facts Obs. 1792;3:105-120.
2
Mythology to reality: case report on a giant cutaneous horn of the scalp in an African American female.从神话到现实:一位非裔美国女性头皮巨大皮肤角的病例报告。
J Plast Reconstr Aesthet Surg. 2014 Jan;67(1):e22-4. doi: 10.1016/j.bjps.2013.08.013. Epub 2013 Aug 22.
3
Giant keratoacanthoma-like cutaneous horn of the upper leg: A case report.
巨大皮肤角:它是冰山一角吗?两例病例报告及文献综述
Indian J Otolaryngol Head Neck Surg. 2022 Dec;74(Suppl 3):5432-5435. doi: 10.1007/s12070-021-02719-1. Epub 2021 Jul 6.
4
A rare case report of graft-versus-host disease-related cutaneous horns of the lower lip.一例罕见的移植物抗宿主病相关下唇皮肤角病例报告。
JAAD Case Rep. 2022 Jan 8;21:59-62. doi: 10.1016/j.jdcr.2021.12.035. eCollection 2022 Mar.
5
Cutaneous horn overlying verrucous carcinoma on face and its dermoscopic characterization.面部疣状癌上的皮肤角及其皮肤镜特征
Indian J Dermatol Venereol Leprol. 2021 May-Jun;87(3):388-390. doi: 10.25259/IJDVL_512_20.
6
A Curious Case of Cutaneous Horn.
Cureus. 2020 Sep 5;12(9):e10253. doi: 10.7759/cureus.10253.
Acta Dermatovenerol Alp Pannonica Adriat. 2010;19(2):29-30.
4
Cutaneous horn: a retrospective histopathological study of 222 cases.皮肤角:222例病例的回顾性组织病理学研究
An Bras Dermatol. 2010 Mar-Apr;85(2):157-63. doi: 10.1590/s0365-05962010000200005.
5
Images in clinical medicine. Squamous-cell carcinoma manifesting as a cutaneous horn.临床医学影像。表现为皮角的鳞状细胞癌。
N Engl J Med. 2008 Aug 28;359(9):e10. doi: 10.1056/NEJMicm075948.
6
Gigantic cutaneous horns of the scalp: lesions with a gross similarity to the horns of animals: a report of four cases.
Am J Surg Pathol. 2002 Jun;26(6):789-94. doi: 10.1097/00000478-200206000-00014.
7
Everard Home, John Hunter, and cutaneous horns: a historical review.伊夫林·霍姆、约翰·亨特与皮角:历史回顾
Am J Dermatopathol. 2001 Aug;23(4):362-9. doi: 10.1097/00000372-200108000-00014.
8
Basal cell carcinoma at the base of cutaneous horn (cornu cutaneum).
Arch Dermatol. 1971 Jul;104(1):97-8.
9
Cutaneous horns of the penis: an approach to management. Case report and review of the literature.阴茎皮角:一种治疗方法。病例报告及文献综述。
J Am Acad Dermatol. 1985 Aug;13(2 Pt 2):369-73. doi: 10.1016/s0190-9622(85)70177-6.
10
A histopathological study of 643 cutaneous horns.643例皮肤角的组织病理学研究。
Br J Dermatol. 1991 May;124(5):449-52. doi: 10.1111/j.1365-2133.1991.tb00624.x.