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避免人工瓣膜病变的瓣膜修复:二尖瓣修复的中期结果

Valve repair to avoid prosthetic valve pathology: Mid-term results in mitral valve repair.

作者信息

Balcı Ahmet Yavuz, Vural Ünsal, Kızılay Mehmet, Dönmez Cevdet, Akansel Serdar, Özdemir Fatih, Aksoy Rezan, Abay Günseli

机构信息

Department of Cardiovascular Surgery, Dr. Siyami Ersek Thoracic and Cardiovascular Surgery Training and Research Hospital, İstanbul, Turkey.

Department of Cardiology, Dr. Siyami Ersek Thoracic and Cardiovascular Surgery Training and Research Hospital, İstanbul, Turkey.

出版信息

Turk Gogus Kalp Damar Cerrahisi Derg. 2018 Jan 9;26(1):14-21. doi: 10.5606/tgkdc.dergisi.2018.14503. eCollection 2018 Jan.

Abstract

BACKGROUND

In this study, we aimed to present our results of mitral valve repair.

METHODS

Between January 2007 and November 2016, a total of 128 patients (72 males, 56 females; mean age 51.8±17.2 years; range 16 to 84 years) who underwent mitral valve repair in our heart center were retrospectively analyzed. There were mitral regurgitation in 86.7% (n=111), mitral stenosis in 7.8% (n=10), and mixed type valve disease in 5.5% of the patients (n=7). Mitral ring annuloplasty was performed in 80.5% (n=103), implantation of the artificial chordae in 36.7% (n=47), open mitral commissurotomy in 13.3% (n=17), and Alfieri procedure in 6.3% (n=8) of the patients. Sixty-two patients (48.8%) underwent isolated mitral valve repair, while concomitant surgical procedures were performed in the remaining patients. Postoperative mean follow-up was 52 months.

RESULTS

Early (30-day) mortality was observed in seven patients due to low cardiac output. There was no mid-term mortality. During follow-up, various degree of mitral regurgitation was detected in 4 patients (3.6%), regurgitation was severe in two of them and these two require reoperation with the replacement of the valve. Patients with a myxomatous valve pathology who underwent isolated valve repair most benefited from valve repair. Patients with isolated mitral stenosis were the most successful group among the patients with a rheumatic etiology. Postoperative echocardiography showed a significant decrease in the left atrial diameter and pulmonary artery systolic pressures (p<0.01).

CONCLUSION

Mitral valve repair can be applied as an effective and safe treatment method in patients in whom the mitral valve anatomy is sufficient for repair. We suggest that each patient with mitral valve pathology should be evaluated in terms of reparability.

摘要

背景

在本研究中,我们旨在展示二尖瓣修复的结果。

方法

回顾性分析2007年1月至2016年11月期间在我们心脏中心接受二尖瓣修复的128例患者(男性72例,女性56例;平均年龄51.8±17.2岁;范围16至84岁)。患者中二尖瓣反流占86.7%(n = 111),二尖瓣狭窄占7.8%(n = 10),混合型瓣膜病占5.5%(n = 7)。80.5%(n = 103)的患者进行了二尖瓣环成形术,36.7%(n = 47)的患者植入了人工腱索,13.3%(n = 17)的患者进行了直视二尖瓣交界切开术,6.3%(n = 8)的患者进行了阿尔菲里手术。62例患者(48.8%)接受了单纯二尖瓣修复,其余患者进行了同期手术。术后平均随访52个月。

结果

7例患者因低心排血量出现早期(30天)死亡。无中期死亡病例。随访期间,4例患者(3.6%)检测到不同程度的二尖瓣反流,其中2例反流严重,这2例需要再次手术更换瓣膜。接受单纯瓣膜修复的黏液瘤样瓣膜病变患者从瓣膜修复中获益最大。单纯二尖瓣狭窄患者是风湿病因患者中最成功的组。术后超声心动图显示左心房直径和肺动脉收缩压显著降低(p<0.01)。

结论

二尖瓣修复可作为二尖瓣解剖结构足以修复的患者的一种有效且安全的治疗方法。我们建议应对每例二尖瓣病变患者的可修复性进行评估。

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