Marotta Dario A, Kesserwani Hassan
Department of Research, Alabama College of Osteopathic Medicine, Dothan, USA.
Neurology, Flowers Medical Group, Dothan, USA.
Cureus. 2020 Jan 14;12(1):e6656. doi: 10.7759/cureus.6656.
The association between sarcoid myopathy and inclusion body myositis is a rare phenomenon that is not well understood. In this case, we present a 46-year-old female with a five-year history of sarcoidosis who became refractory to treatment, experiencing progressive deterioration and muscle wasting. The patient's distribution of muscle weakness did not follow characteristic patterns of inclusion body myositis. Yet, a subsequent deltoid biopsy revealed diagnostic findings typical of inclusion body myositis. This case report reveals an association between treatment-resistant sarcoid myopathy and the evolution of inclusion body myositis in the absence of characteristic clinical findings.
结节病性肌病与包涵体肌炎之间的关联是一种罕见现象,目前尚未得到充分了解。在此病例中,我们报告一名46岁女性,患有结节病5年,治疗效果不佳,病情逐渐恶化并出现肌肉萎缩。患者肌无力的分布不符合包涵体肌炎的典型模式。然而,随后对三角肌进行活检发现了包涵体肌炎的典型诊断结果。本病例报告揭示了在缺乏典型临床表现的情况下,难治性结节病性肌病与包涵体肌炎演变之间的关联。