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描述艾滋病病毒治疗流程中的漏洞:评估坦桑尼亚艾滋病病毒检测与治疗之间的联系。

Characterizing a Leak in the HIV Care Cascade: Assessing Linkage Between HIV Testing and Care in Tanzania.

作者信息

Harklerode Richelle, Todd Jim, de Wit Mariken, Beard James, Urassa Mark, Machemba Richard, Maduhu Bernard, Hargreaves James, Somi Geoffrey, Rice Brian

机构信息

Institute for Global Health Sciences, University of California, San Francisco, San Francisco, CA, United States.

London School of Hygiene and Tropical Medicine, London, United Kingdom.

出版信息

Front Public Health. 2020 Jan 30;7:406. doi: 10.3389/fpubh.2019.00406. eCollection 2019.

Abstract

In Tanzania, HIV testing data are reported aggregately for national surveillance, making it difficult to accurately measure the extent to which newly diagnosed persons are entering care, which is a critical step of the HIV care cascade. We assess, at the individual level, linkage of newly diagnosed persons to HIV care. An expanded two-part referral form was developed to include additional variables and unique identifiers. The expanded form contained a corresponding number for matching the two-parts between testing and care. Data were prospectively collected at 16 health facilities in the Magu District of Tanzania. The records of 1,275 unique people testing HIV positive were identified and included in our analysis. Of these, 1,200 (94.1%) responded on previous testing history, with 184 (15.3%) testing twice or more during the pilot, or having had a previous HIV positive test. Three-quarters (932; 73.1%) of persons were linked to care during the pilot timeframe. Health service provision in the facility carrying out the HIV test was the most important factor for linkage to care; poor linkage occurred in facilities where HIV care was not immediately available. It is critical for persons newly diagnosed with HIV to be linked to care in a timely manner to maximize treatment effectiveness. Our findings show it is feasible to measure linkage to care using routinely collected data arising from an amended national HIV referral form. Our results illustrate the importance of utilizing individual-level data for measuring linkage to care, as repeat testing is common.

摘要

在坦桑尼亚,艾滋病毒检测数据是为了国家监测而汇总上报的,这使得很难准确衡量新诊断出的患者进入治疗环节的程度,而这是艾滋病毒治疗流程中的关键一步。我们在个体层面评估新诊断出的患者与艾滋病毒治疗的关联情况。我们设计了一份扩展的两部分转诊表格,纳入了更多变量和唯一标识符。扩展后的表格包含一个对应编号,用于匹配检测和治疗两部分的信息。数据是在坦桑尼亚马古区的16个医疗机构前瞻性收集的。我们识别出1275名艾滋病毒检测呈阳性的患者记录并纳入分析。其中,1200人(94.1%)对既往检测史做出了回应,184人(15.3%)在试点期间检测了两次或更多次,或者之前艾滋病毒检测呈阳性。在试点期间,四分之三(932人;73.1%)的患者与治疗建立了关联。开展艾滋病毒检测的医疗机构的医疗服务提供情况是与治疗建立关联的最重要因素;在那些无法立即提供艾滋病毒治疗的机构中,关联情况较差。新诊断出感染艾滋病毒的患者及时与治疗建立关联对于最大化治疗效果至关重要。我们的研究结果表明,利用修订后的国家艾滋病毒转诊表格中常规收集的数据来衡量与治疗的关联是可行的。我们的结果说明了利用个体层面数据来衡量与治疗的关联的重要性,因为重复检测很常见。

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