因近视性黄斑裂孔闭合失败导致复发性视网膜脱离病例中黄斑羊膜移植的应用
Use of Epimacular Amniotic Membrane Graft in Cases of Recurrent Retinal Detachment Due to Failure of Myopic Macular Hole Closure.
作者信息
Moharram Hossam M, Moustafa M Tarek, Mortada Hassan A, Abdelkader Mohamed Farouk
出版信息
Ophthalmic Surg Lasers Imaging Retina. 2020 Feb 1;51(2):101-108. doi: 10.3928/23258160-20200129-06.
BACKGROUND AND OBJECTIVE
To study the anatomical and functional outcomes of using epimacular amniotic membrane graft (AMG) to close myopic macular holes (MMHs) in patients with recurrent retinal detachment (RD).
PATIENTS AND METHODS
Fourteen patients with recurrent MMH-RD were enrolled in a single-arm, prospective study. Pars plana vitrectomy with peeling of any residual internal limiting membrane, preserved AMG was placed over the macular hole (MH) after air-fluid exchange, all patient left on 16% of CF.
RESULTS
Fourteen patients (11 females and three males) with an average age of 58.7 years were included; follow-up was 6 months. Thirteen patients (93%) showed retinal reattachment and closure of the hole confirmed by optical coherent tomography. The mean logMAR of best-corrected visual acuity improved to 1.38 compared to 2.2 preoperatively (P < .002, paired t-test), with no serious intraoperative or postoperative complications.
CONCLUSION
Epimacular AMG for MMH-RD is a safe and effective treatment for closure of myopic MHs. [Ophthalmic Surg Lasers Imaging Retina. 2020;51:101-108.].
背景与目的
研究使用黄斑前羊膜移植（AMG）封闭复发性视网膜脱离（RD）患者的近视性黄斑裂孔（MMH）的解剖学和功能结果。
患者与方法
14例复发性MMH-RD患者纳入一项单臂前瞻性研究。行玻璃体平坦部玻璃体切除术，剥除任何残留的内界膜，在气液交换后将保存的AMG置于黄斑裂孔（MH）上，所有患者保持16%的气体填充。
结果
纳入14例患者（11例女性和3例男性），平均年龄58.7岁；随访6个月。13例患者（93%）视网膜复位，光学相干断层扫描证实裂孔闭合。最佳矫正视力的平均logMAR从术前 的2.2提高到1.38（配对t检验，P < 0.002），无严重术中或术后并发症。
结论
对于MMH-RD，黄斑前AMG是一种安全有效的治疗近视性MH闭合的方法。[《眼科手术、激光与视网膜成像》。2020；51：101-108。]
Zotero 插件