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秘鲁中海拔地区儿童和青少年跟骨的超声参考值。

Ultrasound reference values for the calcaneus of children and adolescents at moderate altitudes in Peru.

机构信息

Universidad Católica del Maule, Department of Diversity and Educational Inclusiveness, Talca, Chile.

Universidad Católica de Santa María, Arequipa, Peru.

出版信息

J Pediatr (Rio J). 2021 Jan-Feb;97(1):88-95. doi: 10.1016/j.jped.2019.12.004. Epub 2020 Feb 19.

Abstract

OBJECTIVE

a) Establish reference values for bone parameters by using the speed of sound (SOS, m/s) of broadband ultrasound attenuation (BUA, dB/MHz) and establish a bone quality index (BQI=αSOS+βBUA) for children and adolescents living in a region of moderate altitude, b) compare bone parameters with an international standard (with different ethnic, socio-economic, and lifestyle backgrounds) by using ultrasound of the calcaneus (heel bone) (QUS).

METHODS

A descriptive cross-sectional study was carried out with children and adolescents between the ages of 6.0 and 16.9 years old. The sample was selected randomly. A total of 1322 subjects were studied. Weight, height, and bone parameters, using ultrasound of the calcaneus, were evaluated SOS, BUA, and BQI. Body Mass Index BMI was calculated.

RESULTS

The average age of males was 11.44±0.35 years old, and for females, it was 11.43±0.35 years old. The students in this research showed slightly higher values of SOS, BUA, and BQI for both sexes when compared with the international reference (the 50th percentile). Percentiles were generated (P3, P10, P25, P50, P75, P90, and P97) using the LMS method [median (M), standard deviation (S), and power of the Box-Cox transformation (L)] by age and sex.

CONCLUSION

The students living at a moderate altitude showed slightly higher values in bone parameters in relation to the international reference. This pattern depicted a population with a better state of bone health. The proposed percentiles may be used to categorize adequate to at risk bone parameters based on age and sex.

摘要

目的

a)利用宽带超声衰减(BUA,dB/MHz)的声速(SOS,m/s)为生活在中海拔地区的儿童和青少年建立骨参数参考值,并建立骨质量指数(BQI=αSOS+βBUA),b)利用跟骨超声(QUS)将骨参数与国际标准(具有不同的种族、社会经济和生活方式背景)进行比较。

方法

本研究采用描述性横断面研究,纳入年龄在 6.0 至 16.9 岁之间的儿童和青少年。采用随机抽样方法,共研究了 1322 名受试者。评估了跟骨超声的 SOS、BUA 和 BQI 等骨参数以及体重、身高和体重指数(BMI)。

结果

男性的平均年龄为 11.44±0.35 岁,女性为 11.43±0.35 岁。与国际参考值(第 50 百分位)相比,研究中的学生在两性的 SOS、BUA 和 BQI 值均略高。使用 LMS 方法(中位数(M)、标准差(S)和 Box-Cox 变换的幂(L))按年龄和性别生成了百分位数(P3、P10、P25、P50、P75、P90 和 P97)。

结论

生活在中海拔地区的学生的骨参数值略高于国际参考值。这种模式描绘了一个具有更好骨骼健康状况的人群。所提出的百分位数可用于根据年龄和性别对适当至有风险的骨参数进行分类。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ee7f/9432011/863a6a79d424/gr1.jpg

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