白藜芦醇、β-拉帕醌及其类似物的抗癌潜力。
Anticancer Potential of Resveratrol, β-Lapachone and Their Analogues.
机构信息
Departamento de Nutrição Básica e Experimental, Instituto de Nutrição, Universidade do Estado do Rio de Janeiro, Rio de Janeiro 20550-013, Brazil.
Faculdade de Farmácia, Universidade Federal do Rio de Janeiro, Rio de Janeiro 21941-902, Brazil.
出版信息
Molecules. 2020 Feb 18;25(4):893. doi: 10.3390/molecules25040893.
This review aims to explore the potential of resveratrol, a polyphenol stilbene, and beta-lapachone, a naphthoquinone, as well as their derivatives, in the development of new drug candidates for cancer. A brief history of these compounds is reviewed along with their potential effects and mechanisms of action and the most recent attempts to improve their bioavailability and potency against different types of cancer.
本综述旨在探讨白藜芦醇（一种多酚二苯乙烯）和β-拉帕醌（一种萘醌）及其衍生物作为癌症新药候选物的潜力。本文回顾了这些化合物的简要历史，以及它们的潜在作用和作用机制，以及最近为提高它们针对不同类型癌症的生物利用度和效力而进行的尝试。
Zotero 插件