Yıldırım Metin, Erşatır Mehmet, Poyraz Samet, Amangeldinova Madina, Kudrina Nataliya O, Terletskaya Nina V
Department of Biochemistry, Faculty of Pharmacy, Harran University, Sanliurfa 63050, Türkiye.
Department of Chemistry, Faculty of Art and Science, Cukurova University, Adana 01330, Türkiye.
Plants (Basel). 2024 Aug 18;13(16):2295. doi: 10.3390/plants13162295.
In recent years, the supercritical CO extraction method has gained attention due to its use of environmentally friendly, non-toxic solvents, ability to operate at lower temperatures that do not cause the degradation of bioactive compounds, and capacity for rapid extraction. This method is particularly notable for isolating bioactive compounds from plants. The extracts obtained have shown superior properties due to their activity against diseases such as cancer, which is one of the leading causes of death worldwide. The aim of this study is to provide an in-depth understanding of the supercritical CO extraction method, as well as to discuss its advantages and disadvantages. Furthermore, the study includes specific data on various plant materials, detailing the following parameters: plant name and region, bioactive compounds or compound classes, extraction temperature (°C), pressure (bar), time (minutes), co-solvent used, and flow rate. Additionally, this study covers extensive research on the isolation of bioactive compounds and the efficacy of the obtained extracts against cancer.
近年来，超临界CO萃取法因其使用环保、无毒的溶剂，能够在不导致生物活性化合物降解的较低温度下操作，以及具备快速萃取能力而受到关注。该方法在从植物中分离生物活性化合物方面尤为显著。所获得的提取物因其对癌症等疾病具有活性而表现出优异的特性，癌症是全球主要死因之一。本研究的目的是深入了解超临界CO萃取法，并讨论其优缺点。此外，该研究包括各种植物材料的具体数据，详细说明了以下参数：植物名称和产地、生物活性化合物或化合物类别、萃取温度（℃）、压力（巴）、时间（分钟）、所用共溶剂和流速。此外，本研究涵盖了关于生物活性化合物分离以及所得提取物对癌症疗效的广泛研究。
