• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Kick and kill for HIV latency.

作者信息

Lewin Sharon R, Rasmussen Thomas A

机构信息

The Peter Doherty Institute for Infection and Immunity, The University of Melbourne and Royal Melbourne Hospital, Melbourne, VIC 3000, Australia; Department of Infectious Diseases, Alfred Hospital and Monash University, Melbourne, Australia.

The Peter Doherty Institute for Infection and Immunity, The University of Melbourne and Royal Melbourne Hospital, Melbourne, VIC 3000, Australia.

出版信息

Lancet. 2020 Mar 14;395(10227):844-846. doi: 10.1016/S0140-6736(20)30264-6. Epub 2020 Feb 19.

DOI:10.1016/S0140-6736(20)30264-6
PMID:32085822
Abstract
摘要

相似文献

1
Kick and kill for HIV latency.针对HIV潜伏状态进行清除和杀灭。
Lancet. 2020 Mar 14;395(10227):844-846. doi: 10.1016/S0140-6736(20)30264-6. Epub 2020 Feb 19.
2
HIV latency reversal agents: A potential path for functional cure?HIV 潜伏逆转剂:功能性治愈的潜在途径?
Eur J Med Chem. 2021 Mar 5;213:113213. doi: 10.1016/j.ejmech.2021.113213. Epub 2021 Jan 23.
3
A clue to unprecedented strategy to HIV eradication: "Lock-in and apoptosis".艾滋病根除策略的新线索:“锁定和凋亡”。
Sci Rep. 2017 Aug 21;7(1):8957. doi: 10.1038/s41598-017-09129-w.
4
Effects of Romidepsin on T-Cell Activation, Apoptosis and Function in the BCN02 HIV-1 Kick&Kill Clinical Trial.罗米地辛对 BCN02 HIV-1 杀伤临床试验中 T 细胞激活、凋亡和功能的影响。
Front Immunol. 2020 Mar 20;11:418. doi: 10.3389/fimmu.2020.00418. eCollection 2020.
5
Which therapeutic strategy will achieve a cure for HIV-1?哪种治疗策略能治愈 HIV-1?
Curr Opin Virol. 2016 Jun;18:14-9. doi: 10.1016/j.coviro.2016.02.001. Epub 2016 Mar 15.
6
Eradication of HIV-1 latent reservoirs through therapeutic vaccination.通过治疗性疫苗接种根除HIV-1潜伏库。
AIDS Res Ther. 2017 Sep 12;14(1):45. doi: 10.1186/s12981-017-0177-4.
7
A setback for kick and kill?踢杀疗法受挫?
AIDS. 2019 Apr 1;33(5):N6. doi: 10.1097/QAD.0000000000002148.
8
In vivo activation of latent HIV with a synthetic bryostatin analog effects both latent cell "kick" and "kill" in strategy for virus eradication.用一种合成苔藓抑素类似物在体内激活潜伏的HIV,在病毒根除策略中对潜伏细胞产生“激发”和“清除”作用。
PLoS Pathog. 2017 Sep 21;13(9):e1006575. doi: 10.1371/journal.ppat.1006575. eCollection 2017 Sep.
9
HIV: Shock and kill.艾滋病病毒:休克与杀伤疗法。
Nature. 2012 Jul 25;487(7408):439-40. doi: 10.1038/487439a.
10
Therapeutic Targeting of HIV Reservoirs: How to Give T Cells a New Direction.治疗性靶向 HIV 储存库:如何为 T 细胞指明新方向。
Front Immunol. 2018 Dec 4;9:2861. doi: 10.3389/fimmu.2018.02861. eCollection 2018.

引用本文的文献

1
Advances in HIV Treatment and Vaccine Development: Emerging Therapies and Breakthrough Strategies for Long-Term Control.艾滋病治疗与疫苗研发进展:新兴疗法及长期控制的突破性策略
AIDS Res Treat. 2025 Jul 4;2025:6829446. doi: 10.1155/arat/6829446. eCollection 2025.
2
Anti-HIV-1 HSPC-based gene therapy with safety kill switch to defend against and attack HIV-1 infection.基于造血干细胞的抗HIV-1基因疗法,带有安全杀灭开关以抵御和对抗HIV-1感染。
Mol Ther Methods Clin Dev. 2025 May 15;33(2):101486. doi: 10.1016/j.omtm.2025.101486. eCollection 2025 Jun 12.
3
Immune-mediated strategies to solving the HIV reservoir problem.

本文引用的文献

1
Nowcasting and forecasting the potential domestic and international spread of the 2019-nCoV outbreak originating in Wuhan, China: a modelling study.实时预测和预报源自中国武汉的 2019-nCoV 疫情在国内和国际的潜在传播:一项建模研究。
Lancet. 2020 Feb 29;395(10225):689-697. doi: 10.1016/S0140-6736(20)30260-9. Epub 2020 Jan 31.
2
Problem-based projects in medical education: extending PBL practices and broadening learning perspectives.基于问题的项目在医学教育中的应用:拓展 PBL 实践,拓宽学习视角。
Adv Health Sci Educ Theory Pract. 2019 Dec;24(5):959-969. doi: 10.1007/s10459-019-09917-1. Epub 2019 Oct 22.
3
A preliminary report on the 1952 epidemic of poliomyelitis in Copenhagen with special reference to the treatment of acute respiratory insufficiency.
解决HIV病毒储存库问题的免疫介导策略。
Nat Rev Immunol. 2025 Feb 13. doi: 10.1038/s41577-025-01136-7.
4
Pro-survival roles for p21(Cip1/Waf1) in non-small cell lung cancer.p21(Cip1/Waf1)在非小细胞肺癌中的促生存作用。
Br J Cancer. 2025 Mar;132(5):421-437. doi: 10.1038/s41416-024-02928-9. Epub 2024 Dec 20.
5
Anti-HIV-1 HSPC-based gene therapy with safety kill switch to defend against and attack HIV-1 infection.基于造血干细胞的抗HIV-1基因疗法,带有安全杀伤开关以抵御和对抗HIV-1感染。
bioRxiv. 2024 Nov 13:2024.11.13.623476. doi: 10.1101/2024.11.13.623476.
6
In vivo selection of anti-HIV-1 gene-modified human hematopoietic stem/progenitor cells to enhance engraftment and HIV-1 inhibition.体内选择抗HIV-1基因修饰的人类造血干/祖细胞以增强植入和HIV-1抑制作用。
Mol Ther. 2024 Feb 7;32(2):384-394. doi: 10.1016/j.ymthe.2023.12.007. Epub 2023 Dec 12.
7
The Archer and the Prey: The Duality of PAF1C in Antiviral Immunity.《射手与猎物:PAF1C 在抗病毒免疫中的双重性》。
Viruses. 2023 Apr 22;15(5):1032. doi: 10.3390/v15051032.
8
HIV Latency and Nanomedicine Strategies for Anti-HIV Treatment and Eradication.HIV潜伏以及抗HIV治疗与根除的纳米医学策略
Biomedicines. 2023 Feb 18;11(2):617. doi: 10.3390/biomedicines11020617.
9
Identification of New L-Heptanoylphosphatidyl Inositol Pentakisphosphate Derivatives Targeting the Interaction with HIV-1 Gag by Molecular Modelling Studies.通过分子模拟研究鉴定靶向与HIV-1 Gag相互作用的新型L-庚酰磷脂酰肌醇五磷酸衍生物
Pharmaceuticals (Basel). 2022 Oct 12;15(10):1255. doi: 10.3390/ph15101255.
10
Combination anti-HIV antibodies provide sustained virological suppression.联合抗 HIV 抗体可提供持续的病毒学抑制。
Nature. 2022 Jun;606(7913):375-381. doi: 10.1038/s41586-022-04797-9. Epub 2022 Jun 1.
1952年哥本哈根小儿麻痹症疫情初步报告,特别提及急性呼吸功能不全的治疗
Lancet. 1953 Jan 3;1(6749):37-41. doi: 10.1016/s0140-6736(53)92530-6.