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血液与肠杆菌科细菌的相互作用:溶血、血凝、纤维蛋白溶解。

Interaction of blood with enterobacteriaceae: hemolysis, hemagglutination, fibrinolysis.

作者信息

Roland F P

出版信息

Am J Clin Pathol. 1977 Mar;67(3):260-3. doi: 10.1093/ajcp/67.3.260.

DOI:10.1093/ajcp/67.3.260
PMID:320861
Abstract

One thousand eighty enterobacteriaceae, isolated during a period of three months, were tested for the presence of hemolysis, hemagglutination and fibrinolysis on human erythrocytes and plasma. The fibrinolysis on human erythrocytes and plasma. The Escherichia coli have the greatest diversity of action on the blood. Of 481 strains, 32.9% were hemolytic, 21.9% fibrinolytic, and 10.5% hemagglutinating. Of 190 strains of Klebsiella, 95.2% were fibrinolytic. Of 53 strains of Enterobacter, 90.6% were fibrinolytic, and of 53 strains of Enterobacter hafniae, 66% were fibrinolytic. Of seven strains of Serratia, 28.5% were hemolytic and 14.3% fibrinolytic. The Proteae were mostly fibrinolytic: 60.5% of 141 strains, with three strains being hemolytic and fibrinolytic. Of 19 strains of Citrobacter, 52.6% were fibrinolytic only. Providenica, Salmonella and Shigella did not interact with human blood. The patterns of blood interactions with the different species of Enterobacteriaceae are of value in the evaluation of the pathogenesis of the infections and septicemias they cause. Their study is an essential step in the understanding of the sequence of events leading to severe disturbances of the blood-clotting mechanism.

摘要

在三个月的时间里分离出的1080株肠杆菌科细菌,针对其在人红细胞和血浆上的溶血、血凝和纤维蛋白溶解情况进行了检测。对人红细胞和血浆的纤维蛋白溶解情况进行了检测。大肠杆菌在血液上的作用具有最大的多样性。在481株菌株中,32.9%具有溶血作用,21.9%具有纤维蛋白溶解作用,10.5%具有血凝作用。在190株克雷伯菌中,95.2%具有纤维蛋白溶解作用。在53株肠杆菌中,90.6%具有纤维蛋白溶解作用,在53株哈夫尼亚肠杆菌中,66%具有纤维蛋白溶解作用。在7株沙雷菌中,28.5%具有溶血作用,14.3%具有纤维蛋白溶解作用。变形杆菌大多具有纤维蛋白溶解作用:141株中的60.5%,有3株同时具有溶血和纤维蛋白溶解作用。在19株柠檬酸杆菌中,52.6%仅具有纤维蛋白溶解作用。普罗威登斯菌、沙门菌和志贺菌不与人血液发生相互作用。肠杆菌科不同菌种与血液相互作用的模式在评估它们所引起的感染和败血症的发病机制方面具有价值。它们的研究是理解导致凝血机制严重紊乱的一系列事件的重要一步。

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Interaction of blood with enterobacteriaceae: hemolysis, hemagglutination, fibrinolysis.血液与肠杆菌科细菌的相互作用:溶血、血凝、纤维蛋白溶解。
Am J Clin Pathol. 1977 Mar;67(3):260-3. doi: 10.1093/ajcp/67.3.260.
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引用本文的文献

1
Hemolytic activity of Serratia marcescens.粘质沙雷氏菌的溶血活性。
Arch Microbiol. 1985 May;141(4):371-6. doi: 10.1007/BF00428852.
2
Hemolysin as a marker for Serratia.
Arch Microbiol. 1990;154(3):221-5. doi: 10.1007/BF00248958.