Gudmand-Hoyer E, Simony K
Am J Dig Dis. 1977 Mar;22(3):177-81. doi: 10.1007/BF01072273.
The clinical significance of lactose malabsorption and the individual sensitivity to lactose were investigated in 20 patients with verified lactose malabsorption. Thirteen patients were relieved of all symptoms while seven improved only on a lactose-free dth lactose-free milk but following provocation with increasing amounts of lactose, the tendency to diarrhea and abdominal discomfort increased considerably. Three patients experienced discomfort after provocation with only 5 gl lactose. On provocation with increasing amounts of lactose the seven patients who had not recovered also developed increased abdominal discomfort but none of them developed increased tendency to diarrhea. It is concluded that, in addition to lactose malabsorption, these patients must suffer from ittitable colon with tendency to constipation.
对20例经证实乳糖吸收不良的患者，研究了乳糖吸收不良的临床意义以及个体对乳糖的敏感性。13例患者所有症状均缓解，而7例仅在饮用无乳糖牛奶时症状改善，但在给予递增剂量乳糖激发后，腹泻和腹部不适的倾向显著增加。3例患者仅在给予5克乳糖激发后即出现不适。给予递增剂量乳糖激发后，7例未恢复的患者腹部不适也加重，但均未出现腹泻倾向增加。结论是，除乳糖吸收不良外，这些患者还患有易激结肠且有便秘倾向。
