Department of Pediatrics, Baylor College of Medicine, 6701 Fannin Street, MWT 1010.03, Houston, TX, USA.
Gastroenterol Clin North Am. 2018 Dec;47(4):715-726. doi: 10.1016/j.gtc.2018.07.001. Epub 2018 Sep 28.
Diet plays a significant role for children with functional abdominal pain disorders. A large majority of these children identify at least 1 food that exacerbates their symptoms. Malabsorbed carbohydrates may have both direct and microbiome-mediated physiologic effects. There are several factors associated with carbohydrate symptom generation, including (1) the amount ingested, (2) ingestion with a meal, (3) small intestinal enzymatic activity, (4) consuming the carbohydrate with microorganisms capable of breaking down the carbohydrate, (5) the gut microbiome, and (6) host factors. Therapies include carbohydrate (single and/or comprehensive) restriction, selective prebiotic and/or enzyme supplementation. Fiber supplementation may also be beneficial.
饮食对于功能性腹痛障碍的儿童非常重要。这些儿童中的绝大多数至少能确定 1 种会加重其症状的食物。未被吸收的碳水化合物可能具有直接和微生物群介导的生理作用。有几个因素与碳水化合物症状的产生有关，包括：(1)摄入的量，(2)与餐食一起摄入，(3)小肠酶活性，(4)与能够分解碳水化合物的微生物一起摄入碳水化合物，(5)肠道微生物组，和(6)宿主因素。治疗方法包括碳水化合物（单一和/或综合）限制、选择性益生元和/或酶补充。纤维补充剂也可能有益。
