儿童功能性腹痛障碍的饮食管理最新进展
Update on Dietary Management of Childhood Functional Abdominal Pain Disorders.
机构信息
Department of Pediatrics, Baylor College of Medicine, 6701 Fannin Street, MWT 1010.03, Houston, TX, USA.
出版信息
Gastroenterol Clin North Am. 2018 Dec;47(4):715-726. doi: 10.1016/j.gtc.2018.07.001. Epub 2018 Sep 28.
Abstract
Diet plays a significant role for children with functional abdominal pain disorders. A large majority of these children identify at least 1 food that exacerbates their symptoms. Malabsorbed carbohydrates may have both direct and microbiome-mediated physiologic effects. There are several factors associated with carbohydrate symptom generation, including (1) the amount ingested, (2) ingestion with a meal, (3) small intestinal enzymatic activity, (4) consuming the carbohydrate with microorganisms capable of breaking down the carbohydrate, (5) the gut microbiome, and (6) host factors. Therapies include carbohydrate (single and/or comprehensive) restriction, selective prebiotic and/or enzyme supplementation. Fiber supplementation may also be beneficial.
摘要
饮食对于功能性腹痛障碍的儿童非常重要。这些儿童中的绝大多数至少能确定 1 种会加重其症状的食物。未被吸收的碳水化合物可能具有直接和微生物群介导的生理作用。有几个因素与碳水化合物症状的产生有关，包括：(1)摄入的量，(2)与餐食一起摄入，(3)小肠酶活性，(4)与能够分解碳水化合物的微生物一起摄入碳水化合物，(5)肠道微生物组，和(6)宿主因素。治疗方法包括碳水化合物（单一和/或综合）限制、选择性益生元和/或酶补充。纤维补充剂也可能有益。
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