Zhou Han-Yu, Cheung Eric F C, Chan Raymond C K
Neuropsychology and Applied Cognitive Neuroscience Laboratory, CAS Key Laboratory of Mental Health, Institute of Psychology, Beijing, China; Department of Psychology, University of Chinese Academy of Sciences, Beijing, China.
Castle Peak Hospital, Hong Kong, China.
Neuropsychologia. 2020 Mar 16;140:107396. doi: 10.1016/j.neuropsychologia.2020.107396. Epub 2020 Feb 20.
To integrate auditory and visual signals into a unified percept, the paired stimuli must co-occur within a limited time window known as the Temporal Binding Window (TBW). The width of the TBW, a proxy of audiovisual temporal integration ability, has been found to be correlated with higher-order cognitive and social functions. A comprehensive review of studies investigating audiovisual TBW reveals several findings: (1) a wide range of top-down processes and bottom-up features can modulate the width of the TBW, facilitating adaptation to the changing and multisensory external environment; (2) a large-scale brain network works in coordination to ensure successful detection of audiovisual (a)synchrony; (3) developmentally, audiovisual TBW follows a U-shaped pattern across the lifespan, with a protracted developmental course into late adolescence and rebounding in size again in late life; (4) an enlarged TBW is characteristic of a number of neurodevelopmental disorders; and (5) the TBW is highly flexible via perceptual and musical training. Interventions targeting the TBW may be able to improve multisensory function and ameliorate social communicative symptoms in clinical populations.
为了将听觉和视觉信号整合为一个统一的感知，成对的刺激必须在一个被称为时间绑定窗口（TBW）的有限时间窗口内同时出现。TBW的宽度是视听时间整合能力的一个指标，已发现它与高阶认知和社会功能相关。对研究视听TBW的研究进行的全面综述揭示了几个发现：（1）广泛的自上而下的过程和自下而上的特征可以调节TBW的宽度，促进对不断变化的多感官外部环境的适应；（2）一个大规模的脑网络协同工作，以确保成功检测视听同步性；（3）在发育过程中，视听TBW在整个生命周期中呈U形模式，在青春期后期有一个漫长的发育过程，并在晚年再次反弹变大；（4）TBW扩大是一些神经发育障碍的特征；（5）TBW通过感知和音乐训练具有高度灵活性。针对TBW的干预措施可能能够改善临床人群的多感官功能并减轻社会交流症状。
