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心力衰竭中的骨骼

Bone in heart failure.

机构信息

Institute for Cardiovascular Diseases Dedinje, Belgrade, Serbia.

Faculty of Medicine, University of Belgrade, Belgrade, Serbia.

出版信息

J Cachexia Sarcopenia Muscle. 2020 Apr;11(2):381-393. doi: 10.1002/jcsm.12516. Epub 2020 Feb 22.

Abstract

There is an increasing interest in osteoporosis and reduced bone mineral density affecting not only post-menopausal women but also men, particularly with coexisting chronic diseases. Bone status in patients with stable chronic heart failure (HF) has been rarely studied so far. HF and osteoporosis are highly prevalent aging-related syndromes that exact a huge impact on society. Both disorders are common causes of loss of function and independence, and of prolonged hospitalizations, presenting a heavy burden on the health care system. The most devastating complication of osteoporosis is hip fracture, which is associated with high mortality risk and among those who survive, leads to a loss of function and independence often necessitating admission to long-term care. Current HF guidelines do not suggest screening methods or patient education in terms of osteoporosis or osteoporotic fracture. This review may serve as a solid base to discuss the need for bone health evaluation in HF patients.

摘要

目前,人们对骨质疏松症和骨密度降低的关注度日益增加,不仅绝经后妇女会受到影响,男性也会受到影响,尤其是患有并存慢性病的男性。迄今为止,人们很少研究稳定型慢性心力衰竭(HF)患者的骨骼状况。HF 和骨质疏松症都是与衰老相关的高发综合征,对社会造成了巨大影响。这两种疾病都是导致功能丧失和独立性丧失的常见原因,也是导致住院时间延长的常见原因,给医疗保健系统带来了沉重负担。骨质疏松症最具破坏性的并发症是髋部骨折,其与高死亡率相关,而对于那些存活下来的患者,会导致功能丧失和独立性丧失,通常需要入住长期护理机构。目前的 HF 指南并未建议针对骨质疏松症或骨质疏松性骨折进行筛查方法或患者教育。这篇综述可以为讨论 HF 患者的骨骼健康评估需求提供坚实的基础。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cd99/7113538/1a941291dcc1/JCSM-11-381-g001.jpg

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