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多因素致双心室广泛钙化 1 例

A case of bi-ventricular extensive calcification caused by multiple factors.

机构信息

Dept of Pediatrics, Renmin Hospital of Wuhan University , Wuhan, 430060, Hubei Province, People's Republic of China.

Dept of Endocrinology, The second affiliated hospital of Guangzhou Medical University, Guangzhou, 510000, Guangdong Province, People's Republic of China.

出版信息

BMC Pediatr. 2020 Feb 22;20(1):85. doi: 10.1186/s12887-020-1973-x.

Abstract

BACKGROUND

Extensive myocardial calcification has a low incidence rate, but when the patients do have extensive myocardial cases, the prognosis is usually poor. Several sepsis-related extensive myocardial calcification cases have been reported, but there are cases of biventricular calcifications that are caused by multiple cases besides bacteremia and the treatment for it has a low percentage of success.

CASE PRESENTATION

A 9 year old girl had an extensive biventricular calcification which is caused by multiple factors including multiple organ failure (heart, lung, liver, and kidney), aseptic cardiomyopathy, systemic inflammatory response syndrome, pulmonary hemorrhage, viral encephalitis. In this case study, the massive myocardial calcification present in the patient was classified as dystrophic. After the patient was transferred to the Intensive care unit, a series of rescue treatments such as anti-inflammatory factor storm were implemented to protect the organs. In the end, the patient was rescued from the rescue treatment procedure. After 18 months of follow-up, it was observed that the patient's heart function returned to normal and it was observed that there was no change in myocardial calcification in the patient.

CONCLUSION

In this case study, it showcased a case of the diffused biventricular calcification that caused by multiple factors. Furthermore, the precise role of calcification on cardiac function was largely unknown and there has to be further follow-up observation on the patient.

摘要

背景

广泛性心肌钙化的发生率较低,但当患者确实存在广泛的心肌钙化时,预后通常较差。已有几例与脓毒症相关的广泛性心肌钙化病例报告,但也有因多种原因(除菌血症外)导致双心室钙化的病例,其治疗成功率较低。

病例介绍

一名 9 岁女孩患有广泛的双心室钙化,这是由多种因素引起的,包括多器官衰竭(心、肺、肝、肾)、无菌性扩张型心肌病、全身炎症反应综合征、肺出血、病毒性脑炎。在本病例研究中,患者大量的心肌钙化被归类为营养不良性。患者转入重症监护病房后,实施了一系列抢救治疗措施,如抗炎因子风暴,以保护器官。最终,患者从抢救治疗中获救。经过 18 个月的随访,观察到患者的心脏功能恢复正常,患者的心肌钙化没有变化。

结论

在本病例研究中,展示了一例由多种因素引起的弥漫性双心室钙化病例。此外,钙化对心功能的确切作用尚不清楚,需要对患者进行进一步的随访观察。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d9e/7036240/17248a19df9e/12887_2020_1973_Fig1_HTML.jpg

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