• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

多因素致双心室广泛钙化 1 例

A case of bi-ventricular extensive calcification caused by multiple factors.

机构信息

Dept of Pediatrics, Renmin Hospital of Wuhan University , Wuhan, 430060, Hubei Province, People's Republic of China.

Dept of Endocrinology, The second affiliated hospital of Guangzhou Medical University, Guangzhou, 510000, Guangdong Province, People's Republic of China.

出版信息

BMC Pediatr. 2020 Feb 22;20(1):85. doi: 10.1186/s12887-020-1973-x.

DOI:10.1186/s12887-020-1973-x
PMID:32087707
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7036240/
Abstract

BACKGROUND

Extensive myocardial calcification has a low incidence rate, but when the patients do have extensive myocardial cases, the prognosis is usually poor. Several sepsis-related extensive myocardial calcification cases have been reported, but there are cases of biventricular calcifications that are caused by multiple cases besides bacteremia and the treatment for it has a low percentage of success.

CASE PRESENTATION

A 9 year old girl had an extensive biventricular calcification which is caused by multiple factors including multiple organ failure (heart, lung, liver, and kidney), aseptic cardiomyopathy, systemic inflammatory response syndrome, pulmonary hemorrhage, viral encephalitis. In this case study, the massive myocardial calcification present in the patient was classified as dystrophic. After the patient was transferred to the Intensive care unit, a series of rescue treatments such as anti-inflammatory factor storm were implemented to protect the organs. In the end, the patient was rescued from the rescue treatment procedure. After 18 months of follow-up, it was observed that the patient's heart function returned to normal and it was observed that there was no change in myocardial calcification in the patient.

CONCLUSION

In this case study, it showcased a case of the diffused biventricular calcification that caused by multiple factors. Furthermore, the precise role of calcification on cardiac function was largely unknown and there has to be further follow-up observation on the patient.

摘要

背景

广泛性心肌钙化的发生率较低,但当患者确实存在广泛的心肌钙化时,预后通常较差。已有几例与脓毒症相关的广泛性心肌钙化病例报告,但也有因多种原因(除菌血症外)导致双心室钙化的病例,其治疗成功率较低。

病例介绍

一名 9 岁女孩患有广泛的双心室钙化,这是由多种因素引起的,包括多器官衰竭(心、肺、肝、肾)、无菌性扩张型心肌病、全身炎症反应综合征、肺出血、病毒性脑炎。在本病例研究中,患者大量的心肌钙化被归类为营养不良性。患者转入重症监护病房后,实施了一系列抢救治疗措施,如抗炎因子风暴,以保护器官。最终,患者从抢救治疗中获救。经过 18 个月的随访,观察到患者的心脏功能恢复正常,患者的心肌钙化没有变化。

结论

在本病例研究中,展示了一例由多种因素引起的弥漫性双心室钙化病例。此外,钙化对心功能的确切作用尚不清楚,需要对患者进行进一步的随访观察。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d9e/7036240/17248a19df9e/12887_2020_1973_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d9e/7036240/17248a19df9e/12887_2020_1973_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d9e/7036240/17248a19df9e/12887_2020_1973_Fig1_HTML.jpg

相似文献

1
A case of bi-ventricular extensive calcification caused by multiple factors.多因素致双心室广泛钙化 1 例
BMC Pediatr. 2020 Feb 22;20(1):85. doi: 10.1186/s12887-020-1973-x.
2
Myocardial calcification as a rare cause of congestive heart failure: a case report.心肌钙化作为充血性心力衰竭的罕见病因:一例报告
J Cardiovasc Pharmacol Ther. 2005 Jun;10(2):137-43. doi: 10.1177/107424840501000208.
3
Disseminated Metastatic Tissue Calcification After Orthotopic Liver Transplantation: A Case Report.原位肝移植后弥漫性转移性组织钙化:一例报告
Transplant Proc. 2016 Jan-Feb;48(1):251-4. doi: 10.1016/j.transproceed.2015.12.033.
4
Porcelain heart: a case of massive myocardial calcification.瓷化心脏:一例大量心肌钙化病例
Int J Cardiovasc Imaging. 2006 Feb;22(1):123-6. doi: 10.1007/s10554-005-9006-2. Epub 2005 Jul 23.
5
Hearts of stone: Rapidly progressive left ventricular myocardial calcifications in severe sepsis: Case series.心如顽石:严重脓毒症中快速进展性左心室心肌钙化:病例系列。
J Med Imaging Radiat Oncol. 2024 Apr;68(3):265-268. doi: 10.1111/1754-9485.13624. Epub 2024 Feb 12.
6
A rare case of myocardial calcification secondary to acute myocarditis due to an infection.一例因感染导致的急性心肌炎继发心肌钙化的罕见病例。
Nagoya J Med Sci. 2020 Nov;82(4):775-781. doi: 10.18999/nagjms.82.4.775.
7
Cardiac Calcifications in Adults with Congenital Heart Defects.先天性心脏病成人患者的心脏钙化
Congenit Heart Dis. 2015 Sep-Oct;10(5):396-402. doi: 10.1111/chd.12243. Epub 2015 Jan 7.
8
Novel pathologic manifestation of idiopathic massive myocardial calcification.特发性心肌广泛钙化的新病理学表现。
Cardiovasc Pathol. 2021 Jan-Feb;50:107298. doi: 10.1016/j.carpath.2020.107298. Epub 2020 Oct 17.
9
Rapidly progressive myocardial calcification following sepsis.脓毒症后快速进展的心肌钙化
J Cardiol Cases. 2021 Sep 20;25(3):166-169. doi: 10.1016/j.jccase.2021.08.011. eCollection 2022 Mar.
10
Myocardial calcification: a predictor of poor outcome for myocarditis treated with extracorporeal life support.心肌钙化:体外生命支持治疗心肌炎预后不良的一个预测指标。
J Pediatr Surg. 1994 Apr;29(4):492-4. doi: 10.1016/0022-3468(94)90074-4.

引用本文的文献

1
Myocardial calcification: case reports and a systematic review.心肌钙化:病例报告及系统评价
Eur Heart J Imaging Methods Pract. 2024 Jul 30;2(3):qyae079. doi: 10.1093/ehjimp/qyae079. eCollection 2024 Jul.
2
First Report of Massive Myocardial Calcifications in a Vervet Monkey ().首例食蟹猴心肌内广泛钙化报告()。
Arch Razi Inst. 2022 Oct 31;77(5):2007-2011. doi: 10.22092/ARI.2022.357062.1963. eCollection 2022 Oct.
3
Rapid Onset Development of Myocardial Calcifications in the Setting of Renal Failure and Sepsis.

本文引用的文献

1
Septic myocardial calcification: A case report.感染性心肌钙化:一例报告。
J Forensic Leg Med. 2019 Jul;65:45-47. doi: 10.1016/j.jflm.2019.05.004. Epub 2019 May 11.
2
Myocardial calcification secondary to toxic shock syndrome: a comparative review of 17 cases.中毒性休克综合征继发心肌钙化:17例病例的比较性综述
BMJ Case Rep. 2019 Jan 10;12(1):bcr-2018-228054. doi: 10.1136/bcr-2018-228054.
3
Extensive Myocardial Calcification in Critically Ill Patients.危重症患者的广泛心肌钙化。
肾衰竭和脓毒症情况下心肌钙化的快速发生发展
Radiol Cardiothorac Imaging. 2021 Apr 1;3(2):e200549. doi: 10.1148/ryct.2021200549. eCollection 2021 Apr.
Crit Care Med. 2018 Jul;46(7):e702-e706. doi: 10.1097/CCM.0000000000003130.
4
A proposed role for sepsis in the pathogenesis of myocardial calcification.脓毒症在心肌钙化发病机制中的一种推测作用。
Acta Cardiol. 2017 Jun;72(3):249-255. doi: 10.1080/00015385.2017.1305163. Epub 2017 Mar 30.
5
Myocardial calcifications: pathophysiology, etiologies, differential diagnoses, and imaging findings.心肌钙化:病理生理学、病因、鉴别诊断和影像学表现。
J Cardiovasc Comput Tomogr. 2015 Jan-Feb;9(1):58-67. doi: 10.1016/j.jcct.2014.10.004. Epub 2014 Oct 22.
6
Vesnarinone restores contractility and calcium handling in early endotoxemia.维司力农可恢复内毒素血症早期的心肌收缩力及钙处理能力。
Circulation. 2000 Nov 7;102(19 Suppl 3):III365-9. doi: 10.1161/01.cir.102.suppl_3.iii-365.
7
Left ventricular calcification following resuscitation.
J Intern Med. 2000 Jul;248(1):85-7. doi: 10.1046/j.1365-2796.2000.00588.x.