卫矛科三萜醌的生物学研究

Biological study of triterpenequinones from celastraceae.

作者信息

Gonzáles A G, Ravelo A G, Bazzocchi I L, Jimenes J, Gonzáles C M, Luis J G, Ferro E A

机构信息

Centro de Productos Naturales Organicos Antonio González, Universidad de la Laguna, Canary Islands, Spain.

出版信息

Farmaco Sci. 1988 Jun;43(6):501-5.

PMID:3208892

Abstract

The cytostatic activity of several triterpenequinone methides isolated from Rzedowskia tolantonguensis and Maytenus horrida (Celastraceae) was evaluated against HeLa cell cultures. Their ID50 were determined and compared with those of other related compounds. A preliminary study of the antibacterial activity of the above triterpenequinone methides was also carried out.

摘要

对从托兰通圭斯裂榄（Rzedowskia tolantonguensis）和粗榧（Maytenus horrida）（卫矛科）中分离得到的几种三萜醌甲基化物对人宫颈癌HeLa细胞培养物的细胞生长抑制活性进行了评估。测定了它们的半数抑制浓度（ID50），并与其他相关化合物的ID50进行了比较。还对上述三萜醌甲基化物的抗菌活性进行了初步研究。