Chávez H, Estévez-Braun A, Ravelo A G, González A G
Instituto Universitario de Bio-Orgánica "Antonio González", Universidad de La Laguna, Avda. Astrofísico Fco. Sánchez 2, 38206, Tenerife, Canary Islands, Spain.
J Nat Prod. 1999 Mar;62(3):434-6. doi: 10.1021/np980412+.
The new nortriterpene methylene quinones amazoquinone (1) and (7S, 8S)-7-hydroxy-7,8-dihydro-tingenone (2), and the new norphenolic triterpenes 7,8-dihydro-6-oxo-tingenol (3), 23-nor-6-oxo-tingenol (4), and 23-oxo-iso-tingenone (5) were isolated from Maytenus amazonica. Their structures were elucidated by spectroscopic methods. Compounds 1, 2, 3, and 5 showed low antitumor activity against four cancer cell lines.
从亚马逊美登木中分离得到新的降三萜亚甲基醌类化合物亚马索醌（1）和（7S，8S）-7-羟基-7,8-二氢tingenone（2），以及新的降酚类三萜化合物7,8-二氢-6-氧代tingenol（3）、23-降-6-氧代tingenol（4）和23-氧代异tingenone（5）。通过光谱方法阐明了它们的结构。化合物1、2、3和5对四种癌细胞系显示出低抗肿瘤活性。
