Suppr超能文献

转甲状腺素蛋白淀粉样变心肌病

[Transthyretin amyloid cardiomyopathy].

作者信息

Hansen Peter Riis, Krakauer Martin

出版信息

Ugeskr Laeger. 2020 Feb 3;182(6).

Abstract

Transthyretin amyloid cardiomyopathy (ATTR-CM) resulting from deposition of transthyretin amyloid fibrils in the heart is an underrecognised cause of heart failure in the elderly and is associated with a poor life expectancy. The diagnosis can now be made by radionuclide imaging with bone tracers, provided absence of plasma-cell dyscrasia. Recent evidence has suggested a considerable prevalence of ATTR-CM, and effective treatment has become available. This review summarises these new developments, which have ushered a new era in the detection and clinical management of ATTR-CM.

摘要

由转甲状腺素蛋白淀粉样纤维沉积于心脏所致的转甲状腺素蛋白淀粉样变心肌病(ATTR-CM),是老年人心力衰竭的一个未得到充分认识的病因,且与预期寿命较短相关。目前,在不存在浆细胞异常增生的情况下,可通过使用骨显像剂的放射性核素成像来进行诊断。最近的证据表明ATTR-CM相当常见,且已有有效的治疗方法。本综述总结了这些新进展,它们开创了ATTR-CM检测与临床管理的新纪元。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验