Elston R A, Kent M L, Drum A S
Center for Marine Disease Control, Battelle/Marine Research Laboratory, Sequim, Washington 98382.
Dev Comp Immunol. 1988 Fall;12(4):719-27. doi: 10.1016/0145-305x(88)90047-x.
Experimental studies with hemic neoplasia in the bay mussel indicated that the condition can be transmitted allogeneically with intact whole cells and cell-free homogenate. A differential pathogenesis of the disease in mussels receiving the two different inocula supports the argument that actual cell transplantation occurred. In addition to the first demonstration of the infectious nature of the disease with cell-free homogenates, it was also shown that the disease is transmitted by cohabitation. Remission of the disease occurred in some mussels indicating individual variation in recognition mechanisms.
对海湾贻贝血液肿瘤的实验研究表明，这种病症可通过完整的全细胞和无细胞匀浆进行同种异体传播。接受两种不同接种物的贻贝中该疾病的不同发病机制支持了实际发生细胞移植的观点。除了首次证明无细胞匀浆具有传染性外，还表明该疾病可通过共居传播。一些贻贝出现了疾病缓解，这表明识别机制存在个体差异。
