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两个分离株的全基因组系统发育和分泌蛋白组分析

Whole Genome Enabled Phylogenetic and Secretome Analyses of Two Isolates.

作者信息

Prokchorchik Maxim, Won Kyungho, Lee Yoonyoung, Segonzac Cécile, Sohn Kee Hoon

机构信息

Department of Life Sciences, Pohang University of Science and Technology, Pohang 37673, Korea.

National Institute of Horticultural and Herbal Science (NIHHS), Rural Development Administration (RDA), Naju 58216, Korea.

出版信息

Plant Pathol J. 2020 Feb;36(1):98-105. doi: 10.5423/PPJ.NT.10.2019.0258. Epub 2020 Feb 1.

DOI:10.5423/PPJ.NT.10.2019.0258
PMID:32089665
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7012575/
Abstract

is a fungal pathogen causing scab disease in Asian pears. It is particularly important in the Northeast Asia region where Asian pears are intensively grown. causes disease in Asian pear but not in European pear. Due to the highly restricted host range of , it is hypothesized that the small secreted proteins deployed by the pathogen are responsible for the host determination. Here we report the whole genome based phylogenetic analysis and predicted secretomes for isolates. We believe that our data will provide a valuable information for further validation and functional characterization of host determinants in .

摘要

是一种导致亚洲梨疮痂病的真菌病原体。在亚洲梨密集种植的东北亚地区尤为重要。在亚洲梨中引发病害,但在欧洲梨中不引发病害。由于的宿主范围高度受限,据推测病原体分泌的小蛋白负责宿主识别。在此我们报告基于全基因组的系统发育分析以及分离株的预测分泌组。我们相信我们的数据将为进一步验证和功能表征中的宿主识别因子提供有价值的信息。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a2c/7012575/c9c454e4114b/ppj-36-098f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a2c/7012575/214f420a2156/ppj-36-098f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a2c/7012575/3d56e2439caa/ppj-36-098f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a2c/7012575/65914b435608/ppj-36-098f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a2c/7012575/c9c454e4114b/ppj-36-098f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a2c/7012575/214f420a2156/ppj-36-098f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a2c/7012575/3d56e2439caa/ppj-36-098f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a2c/7012575/65914b435608/ppj-36-098f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a2c/7012575/c9c454e4114b/ppj-36-098f4.jpg

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本文引用的文献

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2
High Contiguity Whole Genome Sequence and Gene Annotation Resource for Two Isolates.两个分离株的高连续性全基因组序列和基因注释资源。
Mol Plant Microbe Interact. 2019 Sep;32(9):1091-1094. doi: 10.1094/MPMI-03-19-0072-A. Epub 2019 Aug 1.
3
Annotated Draft Genome Sequence of the Apple Scab Pathogen Venturia inaequalis.
苹果黑星病菌不等单囊壳菌的带注释基因组序列草图
Microbiol Resour Announc. 2018 Sep 27;7(12). doi: 10.1128/MRA.01062-18. eCollection 2018 Sep.
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A rust fungal effector binds plant DNA and modulates transcription.一种锈菌效应因子结合植物 DNA 并调节转录。
Sci Rep. 2018 Oct 3;8(1):14718. doi: 10.1038/s41598-018-32825-0.
5
Effectors of plant-colonizing fungi and beyond.植物定殖真菌及其他的效应物。
PLoS Pathog. 2018 Jun 7;14(6):e1006992. doi: 10.1371/journal.ppat.1006992. eCollection 2018 Jun.
6
Improved prediction of fungal effector proteins from secretomes with EffectorP 2.0.利用 EffectorP 2.0 提高对分泌蛋白中真菌效应蛋白的预测。
Mol Plant Pathol. 2018 Sep;19(9):2094-2110. doi: 10.1111/mpp.12682. Epub 2018 May 11.
7
Draft genome sequence of , the causal agent of peach scab.桃疮痂病病原菌的基因组序列草图
Stand Genomic Sci. 2017 Dec 2;12:68. doi: 10.1186/s40793-017-0280-0. eCollection 2017.
8
Biology and Epidemiology of Species Affecting Fruit Crops: A Review.影响水果作物的物种的生物学与流行病学综述
Front Plant Sci. 2017 Sep 19;8:1496. doi: 10.3389/fpls.2017.01496. eCollection 2017.
9
Comparative analysis of the predicted secretomes of Rosaceae scab pathogens Venturia inaequalis and V. pirina reveals expanded effector families and putative determinants of host range.蔷薇科黑星病菌不等黑星菌和梨黑星菌预测分泌蛋白组的比较分析揭示了效应蛋白家族的扩展和宿主范围的推定决定因素。
BMC Genomics. 2017 May 2;18(1):339. doi: 10.1186/s12864-017-3699-1.
10
Predicting Secretory Proteins with SignalP.使用信号肽预测分泌蛋白。
Methods Mol Biol. 2017;1611:59-73. doi: 10.1007/978-1-4939-7015-5_6.