Kotzamanoglou K, Tzanakakis G, Michalopoulos E, Stathopoulou M
Department of Ophthalmology, University of Patras, Greece.
Graefes Arch Clin Exp Ophthalmol. 1988;226(6):539-41. doi: 10.1007/BF02169201.
A case of orbital cellulitis caused by mucormycosis developed in a patient subsequent to cataract extraction and during systemic steroid treatment for postoperative complications. Fatal mucormycosis is a rare disease usually beginning with a subcutaneous inflammatory lesion. As the subsequent development of orbital cellulitis is very rare, little has been published on this subject. In cases of subcutaneous mucormycosis, the diagnosis can easily be made by means of histologic examination of the lesion. However, early diagnosis is difficult in cases with orbital involvement, because the most common cause of orbital cellulitis is bacterial. Thus, orbital cellulitis caused by mucormycosis is often wrongly treated with antibacterial agents only, as histologic examination is neither easy nor part of any routine investigation. Therefore, a combined treatment using antibiotics and antifungal agents in immunusuppressed patients with this disease is advocated.
一名患者在白内障摘除术后及因术后并发症接受全身类固醇治疗期间发生了由毛霉菌病引起的眼眶蜂窝织炎。致命性毛霉菌病是一种罕见疾病,通常始于皮下炎性病变。由于随后发生眼眶蜂窝织炎的情况非常罕见,关于这一主题的文献报道很少。在皮下毛霉菌病病例中,通过对病变进行组织学检查很容易做出诊断。然而,在眼眶受累的病例中早期诊断很困难,因为眼眶蜂窝织炎最常见的病因是细菌。因此,由毛霉菌病引起的眼眶蜂窝织炎常常仅错误地使用抗菌药物治疗,因为组织学检查既不容易进行,也不是任何常规检查的一部分。因此,主张对患有这种疾病的免疫抑制患者采用抗生素和抗真菌药物联合治疗。