免疫功能正常儿童的眼眶毛霉病：危险因素、诊断和治疗方法的回顾。
Orbital mucormycosis in immunocompetent children; review of risk factors, diagnosis, and treatment approach.
机构信息
Professor Alborzi Clinical Microbiology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Shiraz University of Medical Sciences, Namazi Hospital, 7193711351, Zand Ave, Shiraz, Iran.
出版信息
BMC Infect Dis. 2020 Oct 19;20(1):770. doi: 10.1186/s12879-020-05460-2.
BACKGROUND
Orbital mucormycosis is a rare but potentially severe and troublesome invasive fungal infection that could be occurred even in healthy individuals. The initial clinical presentation is similar to bacterial pre-septal or septal cellulitis, especially in early stages.
CASE PRESENTATION
Herein, we describe the successful management of a series of five cases presenting with orbital mucormycosis in previously healthy children.
CONCLUSIONS
Orbital mucormycosis is extremely rare in healthy children and maybe life-threatening when diagnosis delayed given a similar clinical presentation with bacterial septal cellulitis. Intravenous antifungal therapy with amphotericin B and timely surgical drainage is live-saving.
背景
眼眶毛霉菌病是一种罕见但潜在严重且麻烦的侵袭性真菌感染，即使在健康个体中也可能发生。最初的临床表现类似于细菌性眶隔前或眶隔后蜂窝织炎，尤其是在早期阶段。
病例介绍
本文描述了成功治疗五例先前健康的儿童眼眶毛霉菌病的情况。
结论
眼眶毛霉菌病在健康儿童中极为罕见，由于与细菌性眶隔蜂窝织炎相似的临床表现，诊断延迟可能会危及生命。静脉内使用两性霉素 B 进行抗真菌治疗和及时的手术引流是救命的。
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