Department of Podiatry, University of Seville, 41009 Seville, Spain.
Int J Environ Res Public Health. 2020 Feb 20;17(4):1359. doi: 10.3390/ijerph17041359.
Pain and fatigue are major clinical manifestations in patients with Ehlers-Danlos Syndrome (EDS). The aim of this study is to measure change of the effects of custom-made foot orthotics on some manifestations related to EDS, such as foot pain, foot functionality, fatigue, and quality of life.
Thirty-six patients with EDS wore foot orthoses for three months. Foot pain, foot-related disability, foot functionality, fatigue, and quality of life were measured using the 11-point Numeric Rating Scale, the Manchester Foot Pain and Disability Index, the Foot Function Index, the Fatigue Severity Score, and the 12-Item Short Form Health Survey questionnaires, respectively, at the beginning and after 3 months.
Participants demonstrated significantly improved foot pain ( = 0.002), disability related to foot pain ( < 0.001), foot functionality ( = 0.001), fatigue ( < 0.007), and mental health-related quality of life ( = 0.016). The physical health-related quality of life did not show significant changes.
The use of custom-made foot orthoses help in the management of the symptoms by participants. This study could contribute to the foot specialists being considered as an additional member in multidisciplinary teams that are trying to develop an approach for patients with EDS.
疼痛和疲劳是埃勒斯-当洛斯综合征（EDS）患者的主要临床症状。本研究旨在测量定制足矫形器对一些与 EDS 相关的表现的影响变化，例如足部疼痛、足部功能、疲劳和生活质量。
36 名 EDS 患者佩戴足矫形器三个月。使用 11 点数字评分量表、曼彻斯特足部疼痛和残疾指数、足部功能指数、疲劳严重程度评分和 12 项简短健康调查问卷，分别在开始时和 3 个月后测量足部疼痛、足部相关残疾、足部功能、疲劳和生活质量。
参与者的足部疼痛（ = 0.002）、与足部疼痛相关的残疾（ < 0.001）、足部功能（ = 0.001）、疲劳（ < 0.007）和心理健康相关的生活质量（ = 0.016）明显改善。身体健康相关的生活质量没有显著变化。
定制足矫形器的使用有助于参与者管理症状。本研究可以为足部专家被视为多学科团队的额外成员做出贡献，该团队试图为 EDS 患者开发一种方法。
