Giggins Oonagh M, Clay Ieuan, Walsh Lorcan
Insight Centre for Data Analytics, University College Dublin, O’Brien Centre for Science, Science Centre East, Belfield, Dublin, Ireland.
Novartis Business Services, Elm Park, Dublin, Ireland.
Digit Biomark. 2017 Jun 12;1(1):14-42. doi: 10.1159/000477384. eCollection 2017 Sep-Dec.
The aim was to conduct a systematic review to examine the literature reporting the validity and reliability of wearable physical activity monitoring in individuals with neurological disorders.
A systematic search of the literature was performed using a specific search strategy in PubMed and CINAHL. A search constraint of articles published in English, including human participants, published between January 2008 and March 2017 was applied. Peer-reviewed studies which enrolled adult participants with any neurological disorder were included. For the studies which sought to explore the validity of activity monitors, the outcomes measured using the monitor were compared to a criterion measure of physical activity. The studies' methodological quality was assessed using an adapted version of the Quality Assessment of Diagnostic Accuracy Studies (QUADAS) framework. Data extracted from each study included the following: characteristics of the study participants, study setting, devices used, study protocol/methods, outcomes measured, and the validity/reliability of measurement produced.
Twenty-three studies examining the validity and reliability of 16 different monitors were included. The identified studies comprised participants with a range of different disorders of neurological origin. The available evidence suggests that biaxial or triaxial accelerometer devices positioned around the ankle produce the most accurate step count measurements in patients with neurological disorders. The findings regarding the reliability and validity of activity counts and energy expenditure are largely inconclusive in this population.
Ankle-worn biaxial or triaxial accelerometer-type devices provide the most accurate measurement of physical activity. However, further work is required in this field before wearable activity monitoring can be more widely implemented clinically. Standardised activity monitoring protocols are required for implementing these devices in clinical trials and clinical practice, and consensus is required as to the reporting and interpretation of derived variables.
进行一项系统综述，以研究报告可穿戴式身体活动监测在神经疾病患者中有效性和可靠性的文献。
在PubMed和CINAHL中使用特定检索策略对文献进行系统检索。应用了对2008年1月至2017年3月期间发表的、包括人类参与者且为英文发表的文章的检索限制。纳入招募患有任何神经疾病的成年参与者的同行评审研究。对于旨在探索活动监测器有效性的研究，将使用监测器测量的结果与身体活动的标准测量方法进行比较。使用诊断准确性研究质量评估（QUADAS）框架的改编版本评估研究的方法学质量。从每项研究中提取的数据包括：研究参与者的特征、研究环境、使用的设备、研究方案/方法、测量的结果以及所产生测量的有效性/可靠性。
纳入了23项研究，这些研究检验了16种不同监测器的有效性和可靠性。所确定的研究包括患有一系列不同神经源性疾病的参与者。现有证据表明，置于脚踝周围的双轴或三轴加速度计设备在神经疾病患者中产生的步数测量最为准确。关于该人群中活动计数和能量消耗的可靠性和有效性的研究结果在很大程度上尚无定论。
脚踝佩戴的双轴或三轴加速度计型设备提供了最准确的身体活动测量。然而，在可穿戴活动监测能够在临床上更广泛地实施之前，该领域还需要进一步开展工作。在临床试验和临床实践中实施这些设备需要标准化的活动监测方案，并且对于派生变量的报告和解释需要达成共识。
