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1
Long-Term Outcomes and Responses to Retreatment in Patients With Melanoma Treated With PD-1 Blockade.接受 PD-1 阻断治疗的黑色素瘤患者的长期结果和再治疗应答。
J Clin Oncol. 2020 May 20;38(15):1655-1663. doi: 10.1200/JCO.19.01464. Epub 2020 Feb 13.
2
Five-Year Survival with Combined Nivolumab and Ipilimumab in Advanced Melanoma.纳武利尤单抗联合伊匹木单抗治疗晚期黑色素瘤的 5 年生存数据
N Engl J Med. 2019 Oct 17;381(16):1535-1546. doi: 10.1056/NEJMoa1910836. Epub 2019 Sep 28.
3
Pembrolizumab versus ipilimumab in advanced melanoma (KEYNOTE-006): post-hoc 5-year results from an open-label, multicentre, randomised, controlled, phase 3 study.帕博利珠单抗对比伊匹单抗用于晚期黑色素瘤（KEYNOTE-006）：一项开放标签、多中心、随机、对照、III 期研究的 5 年随访后结果。
Lancet Oncol. 2019 Sep;20(9):1239-1251. doi: 10.1016/S1470-2045(19)30388-2. Epub 2019 Jul 22.
4
Safety, Efficacy, and Patient-Reported Health-Related Quality of Life and Symptom Burden with Nivolumab in Patients with Advanced Non-Small Cell Lung Cancer, Including Patients Aged 70 Years or Older or with Poor Performance Status (CheckMate 153).纳武利尤单抗治疗晚期非小细胞肺癌患者的安全性、疗效以及患者报告的健康相关生活质量和症状负担，包括 70 岁或以上或体能状态不佳的患者（CheckMate 153）。
J Thorac Oncol. 2019 Sep;14(9):1628-1639. doi: 10.1016/j.jtho.2019.05.010. Epub 2019 May 20.
5
Analysis of the Association Between Adverse Events and Outcome in Patients Receiving a Programmed Death Protein 1 or Programmed Death Ligand 1 Antibody.分析接受程序性死亡蛋白 1 或程序性死亡配体 1 抗体治疗的患者不良事件与结局之间的关联。
J Clin Oncol. 2019 Oct 20;37(30):2730-2737. doi: 10.1200/JCO.19.00318. Epub 2019 May 22.
6
Discontinuation of anti-PD-1 antibody therapy in the absence of disease progression or treatment limiting toxicity: clinical outcomes in advanced melanoma.抗 PD-1 抗体治疗在无疾病进展或治疗限制毒性的情况下停药：晚期黑色素瘤的临床结局。
Ann Oncol. 2019 Jul 1;30(7):1154-1161. doi: 10.1093/annonc/mdz110.
7
Five-year survival outcomes for patients with advanced melanoma treated with pembrolizumab in KEYNOTE-001.KEYNOTE-001 研究中接受派姆单抗治疗的晚期黑色素瘤患者的 5 年生存结果。
Ann Oncol. 2019 Apr 1;30(4):582-588. doi: 10.1093/annonc/mdz011.
8
Neoadjuvant immune checkpoint blockade in high-risk resectable melanoma.新辅助免疫检查点阻断治疗高危可切除黑色素瘤。
Nat Med. 2018 Nov;24(11):1649-1654. doi: 10.1038/s41591-018-0197-1. Epub 2018 Oct 8.
9
Durable Complete Response After Discontinuation of Pembrolizumab in Patients With Metastatic Melanoma.帕博利珠单抗停药后转移性黑色素瘤患者持久完全缓解
J Clin Oncol. 2018 Jun 10;36(17):1668-1674. doi: 10.1200/JCO.2017.75.6270. Epub 2017 Dec 28.
10
Pooled Analysis of Long-Term Survival Data From Phase II and Phase III Trials of Ipilimumab in Unresectable or Metastatic Melanoma.伊匹单抗治疗不可切除或转移性黑色素瘤的II期和III期试验长期生存数据的汇总分析
J Clin Oncol. 2015 Jun 10;33(17):1889-94. doi: 10.1200/JCO.2014.56.2736. Epub 2015 Feb 9.

Is It Safe to Stop Anti-PD-1 Immunotherapy in Patients With Metastatic Melanoma Who Achieve a Complete Response?

作者信息

Davies Michael A

机构信息

Department of Melanoma Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX.

出版信息

J Clin Oncol. 2020 May 20;38(15):1645-1647. doi: 10.1200/JCO.20.00136. Epub 2020 Feb 25.

DOI:10.1200/JCO.20.00136
PMID:32097093
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7238487/
Abstract
摘要